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Biomedical subjects

N W Solomons

Publications and source records attributed to N W Solomons.

187 records · Page 11Linked to original sources
PubMedDate not supplied

The distribution of intestinal helminth infections in a rural village in Guatemala.

Fecal egg count scores were used to investigate the distribution and abundance of intestinal helminths in the population of a rural village. Prevalences of the major helminths were 41% with Ascaris lumbricoides, 60% with Trichuris trichiura and 50% with Necator americanus. All three parasites showed a highly aggregated distribution among hosts. Age/prevalence and age/intensity profiles were typical for both A. lumbricoides and T. trichiura with the highest worm burdens in the 5-10 year old children. For hookworm both prevalence and intensity curves were convex in shape with maximum infection levels in the 30-40 year old age class. Infected females had higher burdens of T. trichiura than infected males in all age classes of the population; there were no other effects of host gender. Analysis of associations between parasites within hosts revealed strong correlations between A. lumbricoides and T. trichiura. Individuals with heavy infections of A. lumbricoides and T. trichiura showed highly significant aggregation within households. Associations between a variety of household features and heavy infections with A. lumbricoides and T. trichiura are described.

Adolescent↗
PubMedDate not supplied

Trace minerals in paediatric gastroenterology: zinc and copper.

A number of aspects of zinc and copper metabolism are relevant in the clinical practice of pediatric gastroenterology. Although the diagnosis of zinc and copper deficiency is problematic, deficiencies and altered metabolism of these two nutrients are seen in a host of hepatic and intestinal diseases of childhood. Several medical and surgical interventions can adversely affect zinc and copper nutriture as well. Continuing scientific research into the biology of zinc and copper will provide new insights into the pathophysiology of pediatric gastrointestinal diseases.

Child↗
PubMedDate not supplied

Lactose intolerance in protein-energy malnutrition: a clinical case study and family study using a hydrogen (H2) breath-analysis test for carbohydrate malabsorption.

A non-invasive, interval sampling hydrogen (H2) breath-analysis test for carbohydrate malabsorption was used in a 3 year-old Guatemalan child with severe protein-energy malnutrition (kwashiorkor) and in this relatives: mother half-sister and step-father to examine genetic and nutritional factors in lactose intolerance in young children. Clinical lactose intolerance was present in the patient on admission, and lactose malabsorption, even of 0.88 g per kg of weight, persisted after complete nutritional recobly due to gastric retention of the substrate. Malabsorption of a physiological dose of lactose, 12.5 g, was detected in the mother and step-father while their daughter exhibited normal growth and development and normal lactose absorption at 8 months of age. The H2 breath test proved to be a sensitive, well-tolerated procedure for both adults and young children. Pitfalls, such as delayed gastric emptying, absence of normal bacterial flora, prior use of antibiotics, must be considered in interpreting H2 breath test results in children.

Adult↗