Biomedical subjects
N W Pirie
Publications and source records attributed to N W Pirie.
Fact and assumption in studies on the origins of life.
Proteins and nucleic acids organise metabolic systems very efficiently. Original forms of life may have depended on less efficient mechanisms which have been superseded in the course of evolutionary selection. Discussion and experiment on the origins of life should therefore not depend on the assumption that substances and mechanisms, now seemingly essential, were essential initially. Instead we should consider what might happen in a few million years on moist mineral surfaces, smeared with bituminous material, and exposed to UV light in a reducing atmosphere in the absence of predators. What little evidence can be gathered from differences in composition and metabolic behaviour between ancient and recently evolved species suggests that the trend in biochemical evolution is towards simplification.
Purification and crystallization of proteins.
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Potential for leaf protein as human food.
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A simple unit for extracting protein in bulk from leaves.
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Food protein sources.
Work on food, planned by the U.M. (Use and Management) Section of the U.K. committe, was limited to sources of protein because we agreed that more problems calling for research were likely to arise in getting adequate supplies of protein than of other types of food. Deer meat can be produced on land too rough and exposed for sheep; parts of the work on their metabolism and food requirements necessitated building a mobile laboratory. The manner in which the nutritive value of maize is affected by changes in the ratios in which the component proteins are present, stimulated similar studies on barley and groundnut. There is good quality protein in coconuts and leaves but its use in human food is restricted by the presence of fibre. Methods for separating protein from fibre and other deleterious components were improved. In cooperation with scientists in India and Nigeria, the potential yield of protein-deficient foods. e.g. cassava, were 'ennobled' by growing micro-organisms on them with the addition of a cheap source of nitrogen.
Terminology in origin of life studies.
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The yields of extracted protein and of residual fiber from potato haulm taken as a by-product.
In July the yield of protein extractable from potato haulm could be 600 kg/ha and the beginning of September it is 200 kg/ha. The yield of fiber containing 1 to 2% N is less affected by maturity. The annual waste of extractable protein, suitable for feeding nonruminants, is about 60,000 tons. The contribution that some small changes in conventional potato husbandry might make to minimizing this waste is discussed.
Some obstacles to eliminating famine.
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Research on leaf protein and its application.
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Retrospect on the biochemistry of plant viruses.
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The production and use of leaf protein.
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Complementary ways of meeting the world's protein need.
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A discussion on anomalous aspects of biochemistry of possible significance in discussing the origins and distribution of life. Introduction.
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Use of plant protein concentrates as human food.
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