Search PubMed⌕ Search

Biomedical subjects

N Vijayan

Publications and source records attributed to N Vijayan.

At least 37 records · Page 2Linked to original sources
PubMed1982

Evaluation of the cell mediated immune response in pigs using 2,4-dinitrochlorobenzene.

An experiment was carried out to measure the cell mediated immune response in pigs by sensitising the animals with 2,4-dinitrochlorobenzene (DNCB). The pigs could be sensitised with one application of DNCB. The appropriate site for application and the sensitising and challenge dose were standardised. The histological response was characteristic of a delayed hypersensitivity reaction.

Animals↗
PubMed1980

Headache.

Explore the source record for details and available documents.

Cluster Headache↗
PubMed1980

Clonazepam treatment of insomnia due to sleep myoclonus.

Nocturnal myoclonus has been identified as a cause of disturbed sleep and excessive daytime fatigue. To our knowledge, no therapy has heretofore been available to adequately control this problem. We identified this problem clinically in two patients; in one, the phenomenon was observed with a polygraphic sleep recording. Small doses of clonazepam, 1 mg, before retiring were found to specifically control the myoclonus and allow sleep patterns to return to normal.

Adult↗
PubMed1980

Periodic lateralized epileptiform complexes (PLEDs) in Creutzfeldt-Jakob disease.

The electroencephalogram (EEG) of three patients with typical Creutzfeldt-Jakob disease (CJD) was characterized by periodic lateralized epileptiform complexes (PLEDs), which persisted and became bilateral. This unusual pattern preceded the characteristic EEG change of CJD. Persistence of PLEDs should suggest the diagnosis of CJD.

Aged↗
PubMed1977

Acetylcholinesterase activity and menstrual remissions in myasthenia gravis.

Menstrually related temporary remissions of myasthenic symptoms are reported to occur in 25 to 50% of female patients. Even though this has been attributed to hormonal changes associated with the menstrual cycle the underlying mechanism of this hormonal influence has remained elusive. The present study demonstrated a cyclical variation in the activity of red cell acetylcholinesterase (EC 3.1.1.7) enzyme (AChE) with a marked reduction at the time of menstrual remission of symptoms of myasthenia. These cyclical changes were abolished by thymectomy. It appears, therefore, that menstrual remission in myasthenia is at least partly due to hormone-induced changes in AChE activity. This process seems to be under the control of the thymus gland.

Acetylcholinesterase↗