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Biomedical subjects

N Vasile

Publications and source records attributed to N Vasile.

At least 109 records · Page 6Linked to original sources

[Computed tomography of the heart: anatomical findings in normal subjects (author's transl)].

Clear images of the chambers of the heart and the vessels can be obtained by rapid scanning with computed tomography, associated with rapid perfusion of a contrast medium. A study in 30 normal subjects demonstrated that it was possible to identify and localize the heart chambers and the large vessels in different planes, and to obtain precise measurements of the various diameters. These results could form the basis for etiological studies of the cardiopathies.

Contrast Media↗

[Radiological diagnosis of ventrycular aneurysms. A report on 36 operated cases (author's transl)].

The value of different radiological examinations in the diagnosis of left ventricular aneurysms following infarcts is assessed using the results obtained in 36 operated cases. By correlating radiological and surgical findings the orientation value of standard examinations can be determined: almost constant cardiomegaly, irregularity of the borders of the heart, and more rarely, myocardial calcification, are significant signs. The two essential examinations are ventriculography and coronarography. Ventriculography can demonstrate anatomical abnormalities (protrusion), or dynamic changes only (hypokinesia, akinesia, systolic expansion). This remarkably reliable examination showed a predominance of anterior and anterolateral aneurisms (87% of cases), and enables definition of the critical cardiac surface area (about 25%) above which the aneurysm is operable. Coronarography shows that the anterior interventricular artery (A.I.V.) is affected in a large proportion (90%) of aneurysms. These two examinations can be used to select those patients suitable for surgery. Results were good and only one death occurred. In the other cases, the disorders of rhythm were reduced and the manifestations of cardiac insufficiency disappeared.

Adult↗

[Cineangiography in adult mitral valve disease. 41 cases of comparison of anatomical with radiological findings (author's transl)].

During the course of their preoperative assessment, 41 patients with severe mitral valve disease underwent left ventricular cineangiography, AP and lateral at rapid speed (100 images per second). This gave a particularly precise anatomical and physiopathological inventory of the lesions, as was confirmed by preoperative findings. The presence of mitral stenosis was confirmed in all cases and an indication of its degree in the majority.

Adult↗

[Factors influencing the results of aortocoronary bypass in a homogeneous series of 125 surgical patients].

A group of 125 patients having undergone aortocoronary bypass by saphenous graft was studied from the point of view of short and medium term results. The following emerged as factors likely to influence these results: --the technique used in the anastamoses and the quality of peroperative myocardial protection; --the presence of hyperlipidaemia; --the restrictive choice of indications in relation to the results of coronary arteriography; --the presence of cardiac insufficiency or an associated valvular lesion. Overall operative mortality was 8 p. cent. Routine ECG's and enzyme studies were carried out to detect postoperative myocardial necrosis. 4 postoperative infarctions without clinical symptoms or signs were detected (2.4 p. cent). 26 patients underwent surgery as an emergency with simultaneous coronary arteriography and surgery in 24. The mortality in this group was not greater (7.6 p. cent) than in the group as a whole. By contrast, mortality was greater in the presence of cardiac insufficiency (25 p. cent) or an associated valvular lesion (16.5 p. cent).

Adult↗

[Emergency aorto-coronary bypass. Indications and results in a homogenous series of 50 patients].

Emergency myocardial vascularization through an aorta-to-coronary by-pass has been extended recently to acute evolutive accidents of coronary artery disease: either to its minor forms, as the menace syndrome, or its more severe forms, such as complicated myocardial infarction. This study aimed at a retrospective analysis of 50 patients, all operated upon as an emergency, by the same surgical team. The problems peculiar to any group of indications, and the practical and theoretical problems posed by extension of this type of emergency surgery were discussed.

Adult↗

[Surgical correction of septal ruptures after recent acute myocardial infarct].

The problems which are raised by surgical correction of a rupture of the septum complicating an acute myocardial infarction are illustrated by a study of 15 patients admitted for resuscitation. Rarely (3 cases) the anatomical abnormality is well tolerated, and a "planned" secondary operative procedure can then be carried out. More often (12 cases) the severity of the circulatory sequelae makes urgent surgery mandatory; these very severe cases have benefited greatly from advances in medical resuscitation, assisted circulation, and operative techniques.

Acute Disease↗

[Abnormal implantation of a coronary artery in a 53-year-old patient. Surgical correction].

In a 53-years old patient complaining of dyspnoea and angina of effort, the coronary arteriography demonstrated ab abnormal implantation of the pulmonary artery into the left coronary-artery. Correlated with the 39 cases of the adolescent and the adult published in the literature, the case reported has some peculiarities: poorness of the auscultatory signs consisting in a mild apical systolic murmur; electrocardiographic pattern of left complete bundle-branch block; presence of massive calcifications visible by X-ray into the lateral, wall of the left ventricle. Coronary arteriography and catherization made it possible to demonstrate a left-to-right shunt by backward-flow revascularization of the left coronary artery starting from the right coronary artery. A simple suture of the implantation foramen of the abnomal coronary artery resulted in increased pressure into this artery and was followed by disappearance of angina during an observation period of 5 months.

Angina Pectoris↗