Search PubMed⌕ Search

Biomedical subjects

N V Zhuravleva

Publications and source records attributed to N V Zhuravleva.

5 recordsLinked to original sources
PubMed1978

[Nature of inhibition of the activity of macromolecular antibodies].

The presence in the organism of an inhibitory factor expressing its activity under conditions of increased macromolecular globulins production (of M-immunoglobulins in particular) was established experimentally. The inhibitory factor depressed the avidity of the macromolecular antibodies; its appearance preceded reduction of the macromolecular protein level in the blood serum. The inhibitory effect of the blood serum in blood letting and vaccination with bacterial antigen is connected with the blood serum albumins, and with increased cystein and sulfhydryl groups concentration.

Agglutinins↗
PubMed1978

Molecular characteristic of antibodies in the blood serum and in the lymph nodes during fractional immunization with small doses of bacterial vaccines.

An experiment on 58 rabbits demonstrated that only macromolecular agglutinins 19S are present in extracts from the lymph nodes after fractional immunization with small doses of typhoid vaccine or some dysentery vaccine. At the same time, antibodies in the blood serum are distributed in fractions of different molecular weight, starting from the 14th day of experiment. It is very probable that this distribution of antibodies is associated with the occurrence in the blood of an inhibitor of the activity of macromolecular antibodies.

Animals↗
PubMed1977

[Several allergic reactions under conditions of functioning of an inhibitor of antibody activity in the body].

Allergization under conditions of functioning an inhibitory factor in the organism was studied by the reaction of leukocytolysis with Tsuverkalov's dysenterin and in the reproduction of hypersensitivity of the immediate type on the Schultz-Dale's model. It was shown that in functioning an inhibitory factor in the organism the degree of leukocytolysis reaction with the dysentery allergen decreased in the immunized animals in parallel with the fall in the serum antibody activity. A depression of the activity of macromolecular sensitizing antibodies was also observed.

Agglutinins↗
PubMedDate not supplied

[Tachyphylaxis].

Explore the source record for details and available documents.

Animals↗