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Biomedical subjects

N V Vasil'eva

Publications and source records attributed to N V Vasil'eva.

15 recordsLinked to original sources
PubMed2003

[Regimens and efficiency of electromagnetic irradiation in patients with sarcoidosis of the respiratory organs].

The efficiency of different regimens of electromagnetic irradiation therapy (MEIT) was analyzed in cases of 87 patients with primary sarcoidosis of the respiratory apparatus. The study resulted in choosing the optimal MEIT regimens with regard for a form of thoracal sarcoidosis. A high efficiency and safety of MEIT, when applied in patients with sarcoidosis of the respiratory apparatus, as well as its advantages versus systemic corticosteroids were demonstrated.

Adult↗
PubMedDate not supplied

[Ophthalmologic symptomatology in children with periventricular leucomalation].

Ophthalmologic symptoms were analyzed in 76 children with periventricular leucomalation (PL). Clinical or functional ophthalmic disorders were detected in 100% of patients. Changes in the optic nerve disc were diagnosed in 93.4% of patients. The syndrome of dilated excavation (SDE), i.e. dilation and cupping of the optic nerve disc combined in all cases with affection of postgenicular visual paths (of optic radiation and/or striatal cortex) verified by neuroradiology, was most frequently (80.3%) encountered in children with PL. Presumably, the progression of SDE is associated with transsynaptic retrograde degeneration conditioned by the hypoxic-ischemic affection of the CNS in the projection of postgenicular visual paths at pre- and perinatal stages. SDE is an important criterion in the diagnosis of lesions of postgenicular visual paths in babies.

Child↗
PubMedDate not supplied

[Pathomorphology of cerebral cryptococcosis in immunodeficiencies of various etiology].

A wide spectrum of pathomorphological changes in the brain was revealed. They reflect various periods of cryptococcal infection under various conditions of immunodeficiency. In cases of brain cryptococcosis in HIV-infection, a significant spread of necrotic changes was noted. The dependence of structural changes severity in the brain on the size of fungal burden is found. It is shown that the disturbance of structural integrity of microvessel wall, its destruction under the influence of cryptococci is a major factor causing penetration of this infection directly into the substance of the brain.

Adult↗
PubMedDate not supplied

[Changes in the composition of anionic membrane phospholipids influence the protein secretion and biogenesis of cell envelope in Escherichia coli].

The secretion of alkaline phosphatase (PhoA) and peculiarities of biogenesis of the cell envelope were studied in Escherichia coli strains HD30/pHD 102 and HDL11 with controlled synthesis of anionic phospholipids, phosphatidylglycerol, and cardiolipin. Inactivation of the pgsA gene encoding the synthesis of anionic phospholipids or changes in the regulation of its expression by an environmental factor caused changes in the metabolism and composition of membrane phospholipids, which resulted in a decrease in the secretion of alkaline phosphatase through the cytoplasmic membrane and an increase in PhoA secretion from the periplasm into the culture medium. A conforming increase was observed in exopolysaccharide secretion, as well as a decrease in the contents of lipopolysaccharide and lipopolyprotein of the outer membrane that determine the membrane barrier properties. The results obtained testify that anionic phospholipids play a significant role in protein secretion and are probably involved in the interrelation between the protein secretion and biogenesis of cell envelope components.

Alkaline Phosphatase↗
PubMedDate not supplied

[The simultaneous synthesis of peptides and oligonucleotides on kaolinite with the participation of aminoacyladenylates].

A simultaneous synthesis of peptides (2-5 residues) and oligonucleotides (3-9 residues) has been carried out on caolinite matrix using amino acids and aminoacyladenylates as substrates. The rate of oligomer synthesis on mineral surface is higher than that in solution. The mechanism of synthesis has been described. The data has been discussed in connection with abiogenesis of two major types of biopolymers, proteins and nucleic acids.

Adenosine Monophosphate↗