Biomedical subjects
Publications and source records attributed to N V Sokratov.
Administration of antithrombin III-enriched plasma to rabbits with acute Masugi nephritis inhibited prothrombinase formation and increased the release of component C3 from the kidneys. This treatment had a cytoprotective effect and was probably followed by dissociation of antigen--antibody complexes.
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Experiments with perfusion of the kidneys in situ in cats demonstrated that excretion by the kidneys into the circulation of the coagulation factors and fibrinolytic agents could be regulated. Acetylcholine decreased the release into the circulation of the hemocoagulating agents and of the antiheparin compounds, but increased the discharge of plasminogen activators from the kidneys. Atropine stimulated the release from the kidneys of tromboplastic agents and antiheparin components, but decreased the excretion of antithrombin compounds. Atropine intensified the fibrinolytic activity of the perfusate insignificantly.
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