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Biomedical subjects

N V Nozdriukhina

Publications and source records attributed to N V Nozdriukhina.

6 recordsLinked to original sources
PubMed2004

[Cerebro-cardial disorders in hemorrhagic stroke].

AIM: To elucidate relationships brain-heart in hemorrhagic stroke depending on the size and location of hematoma and initial state of the heart. MATERIAL AND METHODS: Clinical and paraclinical methods were used in acute and rehabilitation periods in 160 patients with hemorrhagic stroke. RESULTS: Symptoms of cerebrocardial syndrome in hemorrhagic stroke include arrhythmias (tachycardia, bradycardia, extrasystole, cardiac fibrillation, sick sinus syndrome), blocks (transient bundle-branch block), myocardial dystrophy, in IHD--ischemic myocardial disorders up to subendocardial myocardial infarction. Its severity in massive hemispherical hematomas was due to compression of the brain trunk. CONCLUSION: Pathogenesis of cerebrocardial syndrome rests on impaired central autonomic regulation occurring in stroke.

Adult↗
PubMed2000

[Nervous system changes in adrenal failure].

AIM: To study nervous systems in chronic adrenal failure (CAF). MATERIAL AND METHODS: 262 patients with CAF were studied clinically, biochemically and electrophysiologically before and after treatment. RESULTS: The patients were found to have syndromes of vegetovascular dystonia by hypotonic type, syncopal paroxysms, myastenic, minor strokes, dyscirculatory-dysmetabolic encephalopathy, polyneuropathy. A direct correlation was established between the severity and duration of adrenal failure (AF), lowering of adrenal cortex hormones, coefficient Na/K and clinical manifestations of the neurological syndromes. Adequate hormone replacing and symptomatic therapy promoted a regress of neurological disorders in most of the patients especially in mild and moderate AF. CONCLUSION: Adequate therapy corrects neurological disturbances in patients with chronic NN.

Adolescent↗
PubMed1998

[Central regulatory disorders in the clinical picture of the early postoperative period in patients with tumors of the midbrain].

Neurological, clinical, biochemical examinations, electroencephalography, computer and magnetic resonance tomography of the brain of 336 patients with brain stem and para-brain stem tumors resulted in conclusion that nonspecific autonomic-endocrine reaction caused by disorders in central regulation was the main component of early postoperative period. The first type of such disorders included cases with rather stable indices of both hemodynamics and ionic-osmotic homeostasis characterized by favourable course. Unstable hemodynamics and tendency to increase of osmolarity and serum levels of sodium and glucose as well as unfavourable course of this period were typical for the second type.

Adolescent↗
PubMed1998

[The diagnosis, treatment and prevention of early stages of cerebral blood flow insufficiency].

Biomicroscopy of bulbar conjuctiva as well as oencephalography were quite informative for discovery of subclinical manifestations of disorders of cerebral circulation (DCC). That conclusion resulted from the observation of 133 patients with early forms of vascular pathology of brain. Besides, to find the early signs, it was also worth while to perform some biochemical studies (coagulogram, studies of both rheologic properties and lipids of blood). In order to establish discirculatory encephalopathy it was also expedient to use ultrasonic dopplerography and electroencephalography. Efficiency of some medical-prophylactic measures (normalization of the diet, weight, muscular activity, administration of antiatherosclerotic drugs) that prevented the progression of aorta's stenosis was also demonstrated.

Adult↗
PubMed1998

[Role of autonomic nervous system in pathogenesis and clinical manifestation of arterial hypertension in Icenko-Cushing disease].

AIM: To study the role of autonomic nervous system (ANS) in pathogenesis and clinical symptoms of arterial hypertension (AH) in Icenko-Cushing disease (ICD). MATERIALS AND METHODS: Clinical and paraclinical parameters (vegetative reflexes, special tables, 10 words memory and Spilberg's tests, ECG, electroencephalography, computed tomography, MR-tomography, hormonal status) were studied in 48 ICD patients before and after treatment (adenomectomy, irradiation of the hypophysis, adrenalectomy, parlodel, chlotidin chemotherapy). RESULTS: 94.5% of patients with active ICD had blood hypertension and vegetovascular asthenia. There was a trend to cerebrovascular impairment. In spite of biochemical and clinical ICD remission lipothemia persisted in many patients. CONCLUSION: Pathogenesis of blood hypertension in ICD is related to hypersecretion of ACTH and corticosteroids but further progress of the disease depends on phenotypic features of autonomic nervous system and developing defects of CNS.

Adolescent↗