[Methods of evaluating the results of the blast transformation of lymphocytes reaction].
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Biomedical subjects
Publications and source records attributed to N V Mel'nikov.
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Immunoregulatory cell activities were examined in 40 pregnant women suffering from various periodontitis forms. The results evidence that excessive activation of T-lymphocytes and T-helpers may contribute to the pathogenesis of this condition. The data permit using T-lymphocyte functional activity assessment in the diagnosis and prediction of the course of periodontitis.
A modification of A. J. Cunningham method (1965) is proposed. Positive characteristics of the modification are: simplicity and availability of the production of chambers, the possibility of their repeated use, the use of the sealing support for incubation and counting of hemolysis zones. Two series of experiments were performed to determine sensitivity and reproducibility of the modification as compared with the method of N. K. Jerne and A. A. Nordin (1963).