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Biomedical subjects

N V Ermakov

Publications and source records attributed to N V Ermakov.

At least 37 records · Page 2Linked to original sources

[State of the cornea after early surgery of congenital cataract with subsequent contact correction].

Eighteen cases (28 eyes) with congenital cataracts are analyzed. Transciliary lensectomy technique was used for cataract extraction (the ages of the infants at the moment of surgery varied from 3.5 to 16 months), aphakia was corrected by highly hydrophilic soft contact lenses worn during the daytime. The limbic vessels, corneal epithelium, endothelium, and thickness were examined. No changes in the epithelium were revealed. Only in one case a trend to a moderate dilatation of a limbic vessel in the upper segment was seen in the presence of microphthalmia. Analysis of endothelial morphometry data has revealed a universal tendency in all the cases: cell square increased and their density reduced (by 45 and 19%, respectively) immediately after surgery. Wearing of contact lenses was associated with a somewhat rise of the cell count, this count persisting below the norm by 10% on an average. Corneal thickness increased by 0.05 mm after surgery and by 0.03 mm during lens correction.

Age Factors↗

[Endothelium of the donor's transplant after penetrating keratoplasty].

The results of a follow-up of changes in the transplant endothelial cells in 208 patients (209 eyes) in the periods from 1 week to 5 years after surgery helped the authors define the criteria for the choice of donor material with consideration of the endothelial status for various groups of patients. They suggest a method for differential diagnosis of tissue incompatibility reactions and infection recurrences in patients who were operated on for herpes virus keratoiridocyclitis by means of reflecting biomicroscopy of the endothelium. The minimal count of cells necessary for the transplant to remain transparent was estimated.

Cornea↗

[Protective effect on the graft of bioprotectors of the endothelium in reconstructive surgery of the anterior eye segment].

The authors analyze quantitative and qualitative changes in the transplant endothelium after keratoplasty and reconstruction of the anterior segment of the eye (altogether 209 surgeries) in various periods (1 week to 5 years) after surgery with the use of Quilonum and Chonsurid, endothelial protectors. A marked protective action of Quilonum has been noted, that has helped cut down the loss of endothelial cells by 10-12% in open keratoplasty and by 15% in reconstruction of the anterior segment of the eye. Chonsurid is characterized by an immediate protective effect, but in remote periods after surgery its action is cytotoxic.

Anterior Eye Segment↗

[Open auto-keratoplasty and reflected-light microscopy of the endothelium].

Reflecting microscopy of the endothelium is recommended for assessment of the corneal status before open autokeratoplasty and volumic keratoplasty. The density of 1000 per mm2 has been estimated as the transplantation minimum of endothelial cells. The results of autokeratoplasty have been better if the Healon viscous-elastic bioprotector has been employed. The findings of the dynamic follow-up of the endothelial cell density after surgery are presented.

Corneal Transplantation↗

[Secondary implantation of the anterior-chamber intraocular lenses with flexible supportive elements for correction of aphakia].

The authors have designed an anterior-chamber intraocular lens (IOL) with flexible supporting elements and examined the possibility of its application for secondary correction of aphakia. Secondary implantations of such IOLs have been performed in 25 eyes. The implantation has proved to be low-traumatic and effective: the vision acuity has been unchanged or improved in 92% of cases, the loss of endothelial cells has made up 8.5% when the Healon bioprotector has been used and 10.3% without it. Criteria have been developed for the selection of patients for secondary implantation of IOL.

Adult↗