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Biomedical subjects

N V Aleksandrova

Publications and source records attributed to N V Aleksandrova.

12 recordsLinked to original sources

Use of potentiated preparations to relieve alcohol and opium withdrawal syndromes.

The efficiency of potentiated preparations from ethanol and morphine hydrochloride in the therapy of patients with alcohol and opium withdrawal syndromes was compared in an open clinical trial. Potentiated ethanol relieved the major clinical manifestations, possessed hypnagogic properties, and reduced the severity of neurological and vegetative disorders in patients with the alcohol withdrawal syndrome. Potentiated morphine produced the anxiolytic, myorelaxing, and analgetic effects. Test preparations did not cause side effects.

Adult↗

[BCG vaccination: characteristics of drugs and causes of vaccinal complications].

Series of BCG and BCG-M vaccines causing complications in children vaccinated in Russia's areas in 1995 were checked up. All the series met the Russian and international specifications for BCG and BCG-M vaccines. The incidence of postvaccinal lymphadenitis was 5 times less than the limit laid down by an official article. The properties of the agents produced no significant effect on the number and type of postvaccinal complications. The risk for complications was much less when BCG-M was used. The risk factors were defects of intradermal vaccine administration and contaminant abnormalities prior to vaccination and at the moment of local vaccinal response.

Adjuvants, Immunologic↗

[Effect of bile on the amylolytic activity of various biological media].

It has been established in experiments in vitro that bile activates amylase in blood, saliva and homogenates of the pancreas and small intestinal mucosa. Activation was found to depend on the amount of bile added and enzyme origin. It is suggested that bile has a direct effect on conformation of the amylase molecules.

Amylases↗

[Age and infectious psychoses in children and adolescents].

Infectious psychoses were studied clinically in 60 children divided into three age groups: 3-7 years, 7-12 years and 12-17 years. Acute respiratory diseases, influenza, tonsillitis, otitis were the etiologic factors of psychoses. Short-term delirium states characterized by visual and tactile hallucinations prevailed in the first group. Affective-asthenic syndromes prevailed in the second group children. Their psychoses were characterized by both visual and acoustic illusions. Protracted or periodical disorders of the consciousness including psychosensory, senestopathic and depersonalization ones prevailed in the third group.

Adolescent↗

[Changes in carbohydrate digestion enzymes and liver glycogen during heat adaptation].

Adult white rats were exposed daily during 30 days to 2-hour heating (40--41 degrees)--adaptation, and then were transferred to ordinary temperature conditions at 25--27 degrees--desadaptation. The initial period of adaptation revealed a decrease of the liver glycogen content and a relatively constant level of glycemia. A considerable activation of the carbohydrate digestion enzyme systems followed this lowering of energy resources. Metabolic regulatory mechanisms seem to take part in this activation which plays an adaptive role in maintenance of constant glycemia level under these stressful conditions.

Adaptation, Physiological↗

[Initial stages of steel biocorrosion].

Initial stages of corrosion of mild steel induced by Klebsiela rhinoscleromatis BO2 were studied in various media. The effect of the microorganism was detected 8-10 h after inoculation. The number of viable cells were virtually unchanged within one month in all media, but the corrosive activity of the strain decreased. The corrosive activity of microorganisms can be determined by spectrophotometry even only after incubation for 24 h. At a low level of organic substrate, even strong colonization with microorganisms does not inevitably result in a significant damage to metals.

Biodegradation, Environmental↗

[Development of biological methods of combating steel corrosion, induced by aerobic microorganisms].

Cocultivation of degrading microorganisms and their antagonists decreases the corrosion loss of carbon steel by 20 to 80%. It was found that a microorganism can either accelerate or inhibit corrosion, depending on the nutrient. The magnitude of the effect on corrosion depends on the ability of the microorganism to respond to changes in the nutrient-medium composition by releasing acidic or alkaline metabolites.

Bacteria, Aerobic↗

[Increase in the ecological danger upon the use of biocides for fighting corrosion induced by microorganisms].

Five synergistic combinations of biocides were found, among which the combination of kathon + copper sulfate was the most efficient against Serratia marcescens. Depending on the ratio of these biocides, the synergistic effect of this pair allowed 4-20-fold decreases in the effective concentrations. Combinations of biocides with salts (carbonates and phosphates) that facilitate passivation of steel were found, which considerably decreased the corrosion losses of mild steel in comparison to isolated treatment with biocides or salts. The data showed that biocides must be added to corrosion-prone systems simultaneously with the beginning of their exploitation. Otherwise, considerably excessive amounts of biocides or their synergistic compositions are needed.

Bacteria↗