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Biomedical subjects

N Utsumi

Publications and source records attributed to N Utsumi.

At least 73 records · Page 4Linked to original sources

The effect of streptozotocin-induced diabetes on prolyl hydroxylase activity in rat gingiva.

The diabetes resulted in marked decrease in prolyl hydroxylase (EC 1.14.11.2) activity in rat gingiva. Insulin treatment of diabetic rats returned the decreased enzyme activity to the level of normal controls. The results suggest that diabetes decreases the rate of collagen biosynthesis in gingival tissue by inhibiting the hydroxylation of peptidyl proline in collagen precursors.

Animals↗

Prevalence of diabetes mellitus in a rural area of Japan: by 75 g OGTT.

Tests for DM using the 75 g OGTT method (NDDG diagnostic criteria) were performed on 3145 persons living in rural areas of 8 different geographical regions of Japan (from Tohoku to Kyushu regions). Considerable regional difference was observed with western Japan tending to have higher DM and IGT rates than eastern Japan. The DM and IGT prevalence rates (for rural areas in Japan) were 3.9% and 6.9% respectively, and the DM detection rate was 2.8%. Comparison between normals and disturbance of glucose tolerance group (DM and IGT) on the basis of risk factors for atherosclerotic angiopathy showed that those with abnormal findings were definitely more numerous in the disturbance of glucose tolerance group.

Blood Glucose↗