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Biomedical subjects

N Tyagi

Publications and source records attributed to N Tyagi.

33 records · Page 2Linked to original sources
PubMed1990

Serum lactate dehydrogenase isoenzymes in breast tumours.

Total serum LDH and its isoenzymes were estimated in 10 female controls and 30 cases of breast lump (22 malignant, 6 benign and 2 breast abscess). In breast malignancy, there was a significant elevation of total LDH and LDH-3, LDH-4 and LDH-5 isoenzymes with a significant fall in LDH-1 and LDH-2 percentage value. Following therapy, there was a significant elevation in LDH-1 and LDH-2 towards normal with a significant fall in total serum LDH and LDH-4 and LDH-5 isoenzymes. The estimation was found to be helpful in assessing the response of patient to the therapy given.

Breast Neoplasms↗
PubMedDate not supplied

Mesenchymal chondrosarcoma--a case report.

A Case of extraosseous mesenchymal chondrosarcoma occurring in the occipital region in a 26 year old male is being reported. The patient remained free from recurrence on any metastasis even after 2 years of the tumor resection.

Adult↗
PubMedDate not supplied

A histomorphologic and ultrastructural study of the malignant tumours of the renal pelvis.

The study was carried at two different centres. Only 9 cases of primary malignant tumours of the renal pelvis could be collected during the period of 7 years (1984-1990). Renal pelvis malignancies constituted 0.21% of all the malignancies and 12.16% of all the malignant growths of the kidney (9 out of 74 cases). The age of these patients ranged from 24 to 70 years; the mean being 41.7 years. Male/female ratio was 8:1. Common triad of complaints (pain, haematuria and lump) was noticed in 22.2% of patients. Individually they were noticed in 77.8%, 66.7% and 44.4% of patients respectively. Transitional cell carcinoma was the commonest, seen in 7 patients (77.8%) whereas squamous cell carcinoma and adenocarcinoma were noticed in one patient (11.1%) each. Hydronephrosis, chronic pyelonephritis and nephrolithiasis were noticed in 66.7%, 44.4% and 22.2% of patients respectively. Ultrastructural study of urothelial tumours revealed tumour cells in various stages of differentiation with loss of intercellular junctions and dense collection of rough endopasmic reticulum fibrils around the nucleus.

Adenocarcinoma↗