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Biomedical subjects

N Shorr

Publications and source records attributed to N Shorr.

At least 55 records · Page 3Linked to original sources

Histoacryl closure of eyelid skin grafts.

Histoacryl is virtually an ideal tissue glue. It has found application in corneal surgery, oculoplastic surgery, as well as many other surgical fields. A clinical series of 18 patients requiring eyelid skin grafts is presented. Each of the patients had skin grafts placed with a combination of sutures and Histoacryl. No complications were encountered. The postoperative course and results were identical to the authors' experience with skin grafts closed with suture alone. The advantages of Histoacryl skin closure are discussed. Other uses of Histoacryl in oculoplastic surgery are also reviewed.

Adult↗

The transconjunctival approach to the orbital floor and orbital fat. A prospective study.

The transconjunctival approach to the inferior orbit and orbital fat offers the potential advantage of avoidance of scar creation in the lower eyelid skin and anterior lamellae. Complications of this approach, including conjunctival fornix shortening and eyelid margin malposition, have been occasionally reported. We prospectively observed 25 patients undergoing transconjunctival blepharoplasty and orbital floor surgery. Fornix depth, eyelid margin position, and the presence or absence of eyelid retraction were measured preoperatively and at each postoperative visit. No significant permanent change in these parameters was observed. Temporary entropion was observed in two patients; this resolved with conservative treatment. On self-limited suture granuloma was observed. In a subgroup of six patients, the conjunctival incision was closed on one side and left unclosed on the other. No adverse healing was noted on the unclosed side. We conclude that the transconjunctival approach is associated with a low incidence of complications, and that it does not significantly alter the fornix depth or eyelid margin position. A skin incision is avoided. The inferior orbital septum is not violated, greatly reducing the risk of development of lower eyelid retraction.

Adipose Tissue↗

Blindness following blepharoplasty: two case reports, and a discussion of management.

We present two cases of unilateral permanent visual loss following four-eyelid blepharoplasty. Clinical and radiographic evidence suggested orbital hemorrhage was the cause of visual loss in both cases. In particular, electrophysiologic tests indicated that optic nerve dysfunction, and not retinal ischemia, was responsible for loss of vision. Timely orbital decompression is the cornerstone of managing these dramatic cases.

Blindness↗

Orbital inflammation and optic neuropathies associated with chronic sinusitis of intranasal cocaine abuse. Possible role of contiguous inflammation.

Three cases of long-standing intranasal cocaine abuse were associated with orbitopathy or optic neuropathy. All three cases were characterized by chronic sinusitis. Histopathologic examination of involved sinus and orbital tissues revealed chronic and acute nonspecific inflammation, with no evidence of unusual infections or of idiopathic midline destructive disease. In two of the cases, there was radiographic evidence of contiguous orbital inflammation associated with sinusitis. The inflammatory orbital process in these two cases was steroid responsive, but in one case recurrent inflammation occurred in response to steroid tapering. One patient suffered a complete loss of vision in the involved eye due to fulminant orbital inflammation and optic nerve dysfunction.

Adult↗

Complications of blepharopigmentation.

Blepharopigmentation is a commonly performed procedure with a very low rate of reported complications. We present three complications of the permanent eyeliner procedure: two cases of longlasting pigment fanning, and one case of eyelid margin necrosis with cilia loss and secondary cicatricial entropion. These complications may be related to placement of the pigment too deeply, or to overapplication with tissue maceration. Care should be taken to avoid through-and-through eyelid margin penetration, and to limit the number of needle penetrations to no more than is necessary at each application site.

Adult↗

Nasolacrimal drainage system obstruction after orbital decompression.

We reviewed 123 cases of orbital decompression in 63 patients with dysthyroid ophthalmopathy. Of 90 cases of transantral ethmoidal orbital decompression, 14 (16%) resulted in epiphora. The tearing began between 11 and 18 months after surgery. All patients had obstruction distal to the common internal punctum. The delayed onset suggested progressive cicatricial obstruction of the nasolacrimal drainage system. Damage to adjacent tissues probably caused scarring to extend into the system.

Cerebrospinal Fluid Rhinorrhea↗

Free autogenous "pearl fat" grafts to the eyelids.

Free autogenous "pearl fat" grafts of 5-6 mm in diameter are used as a method of soft tissue augmentation for the eyelid. This method is useful in restoring eyelid contour defects, separating the eyelid lamella to lower the upper eyelid crease, and augmenting eyelids in anophthalmos. Graft survival is variable and pretreatment of fat with insulin is used in an attempt to prolong fat survival. The rationale, indications, and surgical procedure are discussed.

Adipose Tissue↗

Medial entropion following orbital decompression for dysthyroid ophthalmopathy.

We found medial entropion of the lower eyelid to be common following orbital decompression for dysthyroid opthalmopathy. In our series significant postoperative medial entropion was noted in 14 of 69 patients, an incidence of 20%. Only four of these patients had entropion severe enough to require surgery (6%). Before orbital decompression, only one patient was found to have significant medial entropion (1.4%). Analysis of associated factors disclosed a positive relation between the amount of operative proptosis reduction and the degree of postoperative medial entropion. A strong correlation was also observed with the type of approach; transantral surgery was much more likely to be associated with significant postoperative medial entropion than was transconjunctival surgery. We suggest that the inferomedial displacement of the muscle cone that follows orbital decompression results in a force vector, transmitted through the lower eyelid retractors and capsulopalpebral ligament, that intorts the medial lower eyelid. Medial entropion in this setting often coexists with lower eyelid retraction, and if a "spacer" of sclera or ear cartilage is to be inserted into the lower eyelid, it should be carried into the medialmost portion of the eyelid to recess the posterior lamellae, including the medial retractors, and allow the eyelid margin to return to its normal anatomic position.

Entropion↗

Laser treatment of juvenile hemangioma.

Capillary hemangioma in the infant may result in amblyopia, refractive error, or strabismus, and is often disfiguring. Treatment is challenging with respect to maintaining vision, as well as preserving function of the eyelids and ocular adnexa and obtaining the best possible cosmetic outcome. Neodymium-YAG laser photocoagulation may be a useful modality for the treatment of these lesions. We review the characteristics of the three types of lasers currently in wide use in skin surgery, with particular emphasis on their applicability for treatment of juvenile hemangioma. A possible role for the Nd-YAG laser in the management of these tumors is suggested.

Evaluation Studies as Topic↗

Tarsoconjunctival grafts for upper eyelid cicatricial entropion.

Many surgical procedures have been described for correction of cicatricial entropion of the upper eyelid. However, many of them fail to address the altered anatomy responsible for cicatricial entropion, which may lead to excessive scarring, eyelid margin malposition, or blepharoptosis. Tarsoconjunctival grafts provide a strong and permanent buttress to correct the scarring of the posterior eyelid margin that characterizes cicatricial entropion. They provide a smooth mucosal surface to interface with the corneal tear film. Depending on the circumstances, we use free ipsilateral, free contralateral, or sliding "bucket handle" tarsoconjunctival grafting. Mucosal grafts are rarely needed. Blepharoptosis is avoided by conservative dissection in the supratarsal space, sparing most of the attachments of the levator aponeurosis.

Cicatrix↗

Cyanoacrylate-fixed silicone sleds in the orbit. An animal model.

Subperiosteal wedge-shaped sleds of various materials have been used in treating the enophthalmic anophthalmic socket and in correcting the enophthalmic seeing eye. Posterior fixation of the sled may be difficult, as the sled tends to migrate anteriorly. Tissue adhesives were studied as a fixation method for silicone sleds in rabbit orbits. Gross examination revealed that the sleds were secured in position until well encapsulated. Butyl 2-cyanoacrylate (Histoacryl Blue) induced minimal inflammation, while ethyl cyanoacrylate (Crazy Glue) caused a giant-cell response.

Animals↗

Management of ptosis in chronic progressive external ophthalmoplegia.

Patients with chronic progressive external ophthalmoplegia (CPEO) are often disabled by ptosis; however, conventional ptosis surgery may induce lagophthalmos and exposure keratitis. Ten patients with CPEO underwent ptosis correction via bilateral frontalis suspensions, using monofilament synthetic material. Three of these patients were also treated with lower eyelid horizontal tightening. The frontalis sling was adjusted to provide a firm linkage between the eyebrow and eyelid, but was loose enough to allow eyelid closure when the frontalis muscle is relaxed. All patients experienced lessening of ptosis and relief from visual obstruction. One patient required reoperation of one eyelid for undercorrection. No lagophthalmos or corneal complications occurred. The rationale for treatment, preoperative evaluation, and operative procedure in CPEO is discussed herein.

Adult↗

A case of prostatic carcinoma metastatic to the orbit diagnosed by fine needle aspiration and immunoperoxidase staining for prostatic specific antigen.

A fine needle aspiration biopsy of the mass guided by computerized tomography was performed on a 65-year-old male with unilateral proptosis, inflammation, and diplopia in downgaze. Using an immunoperoxidase technique for prostatic specific antigen, the cytologic specimen stained positively. Subsequently, a needle biopsy of the prostate gland confirmed the presence of a moderately well-differentiated infiltrating carcinoma.

Aged↗

Floppy eyelid syndrome and blepharochalasis.

Floppy eyelid syndrome and blepharochalasis may represent a spectrum of one underlying disease. Two patients with floppy eyelid syndrome and one with blepharochalasis shared important clinical similarities. All three patients displayed eyelid laxity associated with papillary conjunctivitis and ocular surface abnormalities. Histopathologic findings were similar in the three cases, characterized by chronic conjunctival inflammation with normal tarsal collagen. In all three patients surgical horizontal eyelid shortening led to improvement in symptoms and findings.

Adult↗

The four stages of surgical rehabilitation of the patient with dysthyroid ophthalmopathy.

A logical and comprehensive program for the total ophthalmic rehabilitation of the dysthyroid patient is described. Surgical rehabilitation is always considered in four stages: orbital decompression, extraocular muscle surgery, eyelid margin repositioning, and blepharoplasty. Each stage must be considered in order. By observance of this protocol, repeat surgical procedures can be minimized.

Adult↗