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Biomedical subjects

N S Shvydko

Publications and source records attributed to N S Shvydko.

At least 37 records · Page 2Linked to original sources

[The specificity of the deposition of intratracheally administered plutonium in different skeletal bones with a change in iron homeostasis].

A study was made of the distribution of plutonium-239 injected intratracheally within different bones of the skeleton, the iron status in the blood being changed. The iron preparation caused a 2.5-3-fold decrease in the plutonium loading onto cancellous bone tissue that displayed, in ordinary conditions, a higher tropism to the radionuclide than a cortical highly mineralized bone did.

Animals↗

[The levels of soil pollution with plutonium isotopes in the Bryansk Oblast (following the accident at the Chernobyl Atomic Electric Power Station)].

The estimates of plutonium concentration in soils of Western regions of Bryansk (Krasnogorsky, Novozybkovsky, Zlynkovsky and Klintsovsky) are presented. The levels of soil contamination with plutonium within the regions examined vary by 4-5 times, although no definite geographical direction of pollution intensity within the territory examined is noted. The cumulative concentration of isotopes (238Pu, 239Pu, and 240Pu) varies within 21-112 Bq/kg.

Accidents↗

[The applicability of the concept of morpho-physiologic metabolic factors to the modification of the distribution of 239Pu deposited in the respiratory organs].

At the stage of intensive resorption of plutonium from lungs to blood the competitive per os administration of an iron preparation increased plutonium excretion from blood. As a result, soft tissues were enriched with plutonium at an early stage of metabolism. However, at the end of the experiment (30 days) the radionuclide content of soft tissues dropped to control values. Simultaneously, the share of plutonium deposited in bone tissue decreased considerably and that of the radionuclide eliminated from the body increased throughout the entire period of observation.

Administration, Oral↗

[The effect of iron on the excretion by rats of intratracheally administered plutonium-239].

A study was made of the effect of ferric citrate on excretion of intratracheally administered plutonium-239. The preparation used permitted to increase the radionuclide excretion via the gastrointestinal tract by 1.8 times as compared to the control. The positive effect of the iron preparation was maximally displayed between days 4 and 11 following administration: the value of the increase was 2.2.

Animals↗