[Protective properties of polyethylene oxide during low-temperature preservation of bone marrow].
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Biomedical subjects
Publications and source records attributed to N S Pushkar'.
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To treat postoperative hypothyrosis, use was made of implantation of autologous thyroid tissue preserved and stored for 4 to 12 months before patients developed hypothyrosis. It was established that the treatment was followed by an increase in 131I accumulation in the body at the expense of its accumulation by the implant and stimulation of the process in the stump. This was paralleled by a considerable rise in T3 and T4 and reduction in TTH in the patients' blood. The patients substantially improved while the manifestations of hypothyrosis disappeared. The effects detected could be seen throughout the whole observation period (up to 18 months). The patients did not require any additional drug treatment. The data provided attest to the efficacy of autoimplantation of cryopreserved thyroid parenchyma for the treatment of postoperative hypothyrosis.
It is shown that exogenic nucleic acids (RNA, DNA) have a stimulating effect on the proliferative activity of the restored myelokaryocytes in the organism of the irradiated recipients. The stimulating effect depends on the type of nucleic acid, time of administration and dose of the preparation.
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