Dietary fiber and colonic function.
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Biomedical subjects
Publications and source records attributed to N S Painter.
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Sterculia with and without a smooth-muscle relaxant (alverine citrate) had similar beneficial effects on constipation and reduced the transit times in diverticular disease. Intracolonic pressure, however, varied with the preparation used. Though both preparations relieved the symptoms of diverticular disease, the one containing alverine citrate was more effective. Part of the mode of action of bran may be to relax the smooth muscle of the gut, since its actions were more comparable to those of sterculia plus alverine citrate than to those of sterculia alone.
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This paper describes the pathogenesis, aetiology, epidemiology and the historical emergence of diverticular disease as a clinical problem. The symptoms of the uncomplicated disease can be treated successfully and cheapli with a high fibre diet including miller's bran. The method of giving bran and its results are described. The adoption of a high fibre diet lessens the need for surgery in diverticulitis and the author believes that it could prevent the appearance of the condition in future generations.