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Biomedical subjects

N S Milovidova

Publications and source records attributed to N S Milovidova.

8 recordsLinked to original sources

[Morphologic changes in the ovary during ovulation].

The authors' data and those from the literature on composition of the preovulatory follicle of the mammalian ovary and its morphologycal changes at ovulation are presented. Structure of some follicular components such as the granular layer, internal Ovulation is demonstrated to be accompanied with increasing interstitial edema and cellular dissociation in all structural elements of the follicle. Successive stages in the rearrangement of the follicular membranes are analysed by means of the transmission and scanning electron microscopy. Some hypotheses on main factors and mechanisms participating in ovulation are discussed.

Animals↗

[Ultrastructural organization of the mammalian pineal body during postnatal ontogenesis].

Ultrastructural organization of the components composing the mammal pineal gland is analyzed on the basis of literature data and personal observations. Variations in the form, size and ultrastructural organization of the cellular elements in the pineal gland--pinealocytes, interstitial and glial cells--are discussed. The problem of dark and light pinealocytes is considered as a part of a general biological problem on the presence of dark and light cells as a reflection of the law on "intermittent activity of functional structures". An attention is paid to the organization of the microcirculatory bed and pericapillary space to the peculiarities of the secretory process in the organ. Dynamic changes in the cytologic organization of pinealocytes and other components of the organ in the postnatal ontogenesis are presented in detales.

Animals↗

[Morphofunctional characteristics of the thyroid gland under conditions of decreased adrenergic mediation].

Histophysiology of follicular thyreocytes of the thyroid gland of mice (line Bal) was studied under depressed function of the sympathetic nerve system (antibodies were introduced to the growth factor of the nerves). The data of electron microscopic analysis, quantitative cytochemical investigation and biochemical estimation of iodine binding with blood plasma proteins, demonstrated changes during secretory process in the follicular thyreocytes and in functional intensity of the whole gland. Stimulating effect of the sympathetic nervous system on the releasing process of the thyroid hormones is suggested.

Animals↗

[The state of the nuclear apparatus of the thyroid gland under conditions of hypofunction of the sympathetic division of the nervous system].

A study was made of the effect of the sympathetic portion of the nervous system on the thyrocyte metabolism. Such morphological criteria as the volume of the thyrocyte nuclei, the amount of DNA in them and structural analysis were used. Three volumetric classes of the nuclei with a different morphological picture were detected in control animals. In depression of the sympathetic portion of the nervous system by administration of antibodies to the growth factor of the nerves there was seen a reduction of the mean nuclear volume and displacement of the volumetric classes in the direction of increase in the quantity of smaller nuclei; electron microscopic studies demonstrated changes in the shape and structure of the nuclei. There were no variations in the amount of DNA.

Animals↗

[The role of the nervous factor in regulation of oxygen supply to the small intestine].

The experimental model of rat bilateral subdiaphragmatic stem vagotomy was used to study the role of parasympathetic nervous system in regulation of circulation and oxygen supply to the small intestine. Cut of the vagus nerves is shown to cause redistribution of the blood flow between gastroduodenal organs, to slow down local circulation, to reduce oxygen tension in the muscular lining of the jejunum, to raise water content in the wall and change magnetorelaxational characteristics. Morphologically this manifested in altered arteriolar and capillary configuration, dilation of the capacity microvessels, dystrophia of microvessel wall, red cell aggregation in capillaries and venules, defective permeability of the vascular wall. The above indices changed most 7 and 30 days after vagotomy. It is evident that impaired vagus innervation produces secondary circulation hypoxia in the small intestine.

Animals↗