Biomedical subjects

N S Kumar

Publications and source records attributed to N S Kumar.

57 records · Page 4Linked to original sources

PubMedDate not supplied

Large thrombus in the pulmonary arteries in a case of atrial septal defect-Eisenmenger syndrome.

A 41-year-old man with atrial septal defect-Eisenmenger syndrome presented with progressively worsening breathlessness. The echocardiogram, computerized tomographic scan and magnetic resonance imaging of the thorax showed dilated pulmonary arteries and large thrombi in the right and left pulmonary arteries. Contrast-enhanced computerized tomographic scan was better than magnetic resonance imaging in picking up the thrombus. The possibility of in situ thrombus formation was considered more likely than thromboembolism, as there were none of the acute symptoms expected with the embolization of such large thrombi.

Adult↗

PubMedDate not supplied

Bedside urinalysis in untreated leprosy patients.

The study included 53 patients of untreated leprosy attending University Hospital, Banaras Hindu University during study period of 1 1/2 years. The various types of leprosy included 9,14,16 and 14 cases of tuberculoid, borderline, lepromatous and leprosy with type II reaction respectively. Majority of the patients were below the age of 49 years with male preponderance. 66.04% of patients came from the rural area. Painful micturation (dysuria) (13.20%) was the commonest urinary complaint recorded on enquiry. Specific gravity of urine did not show any change. Abnormal proteinuria was noted in 16.98%, 11.32%, 7.54% and 3.77% of patients of leprosy with reaction, lepromatous, borderline and tuberculoid group respectively. Significant haematuria, pyuria and epithelial cells were noted in all the groups. Haematuria was recorded in focal segmental Glomerulonephritis (GN), mesangioproliferative and diffuse endocapillary Glomerulonephritis (GN) incidence of which was 7.89%, 7.89% and 5.26% respectively in the biopsy tissue. Significant pyuria was noticed in all the groups except minimal change GN.

Adult↗

PubMedDate not supplied

Dietary carbohydrates and synthesis and secretion of apolipoprotein B-containing lipoproteins in rat hepatocytes.

The influence of glucose-, sucrose- and starch-containing diets on the synthesis and secretion of lipoprotein in the density range of very-low-density lipoproteins (VLDLs) and low-density lipoproteins (LDLs) was studied via primary cultures of rat hepatocytes. Apolipoprotein B secreted by hepatocytes from rats fed a sucrose diet was significantly more than in rats fed starch or glucose. This was further confirmed by pulse labeling with [3H]leucine and chase study. Increased synthesis and secretion of cholesterol in lipoproteins of the VLDL and LDL density range and decreased synthesis and secretion of triglyceride in the VLDL fraction were observed in hepatocytes from sucrose-fed animals compared with those fed glucose. This indicates that the VLDL secreted by hepatocytes from sucrose-fed animals was richer in cholesterol but poorer in triglycerides than from glucose/starch- and glucose-fed animals. These findings also suggest an increase in the synthesis and secretion of apolipoprotein B by hepatocytes on sucrose feeding, indicating an association with an increase in cholesterogenesis.

Animals↗