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Biomedical subjects

N S Jaffe

Publications and source records attributed to N S Jaffe.

At least 55 records · Page 3Linked to original sources

The results of intracapsular cataract extraction with a Binkhorst iris clip lens implant 34 to 40 months after surgery.

A series of 300 consecutive intracapsular cataract extractions with a Binkhorst iris clip lens implant was evaluated 34 to 40 months after surgery, except for those patients who died before this time (30 patients) and those lost to follow-up (13 patients). Eighty-eight percent of the 257 patients achieved 20/40 or better visual acuity. The results were similar to those series previously reported by the authors where the final examination time for each patient was not uniform.

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Lens implantation, miosis, and glaucoma.

In a series of 1,079 patients, average age 76.3 years, 48 eyes required an iridoplasty for chronic miosis and, of these, visual acuity was 6/12 (20/40) or better postoperatively in 89.6% (43). In those patients with glaucoma, the control of intraocular pressure was the same or better than post-operative levels in 83.3% (15) of patients. Lens implantation was not contraindicated in the miotic patient if adequate iris surgery was performed before both cataract extraction and implant insertion. When there was concomitant glaucoma, lens implantation was likewise not contraindicated if the glaucoma was well controlled.

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Lens implantation and diabetes mellitus.

In a series of 1,160 implant cases, 82 patients were diabetic. In this subgroup, lenses were implanted in 87 eyes, and a visual acuity of 6/12 (20/40) or better was obtained in 77 (88.6%) of the patients, which compared well with the nondiabetic control group of 1,078 cases. Only patients with normal fundi or minimal background retinopathy were operated on, and the visual results obtained were independent of the diabetic medical management.

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The changing scene of intraocular implant lens surgery.

A review of lens implant surgery using different implant styles and both methods of cataract extraction revealed that there is little difference in the final visual acuity regardless of which implant or cataract technique is used. There appears to be a higher rate of cystoid macular edema with the intracapsular technique and a higher rate of corneal edema with the extracapsular technique. A modern attitude toward this technologic explosion insists more than ever on conventional points of view regarding patients' needs.

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Dislocation of Binkhorst four-loop lens implant.

A consecutive series of 1,093 Binkhorst four-loop lens implantations was used to examine the problem of dislocation of implants used in intracapsular cataract extractions; emphasis of the study was on the need for suture fixation. Transiridectomy suture fixation was used in 497 procedures, no suture was used in 403 procedures, and a simple iris suture technique was used in 193 procedures. Although the transiridectomy suture fixation procedure had the lowest percentage of dislocations, the iris suture technique is considered safer. Suture fixation is recommended for Binkhorst four-loop implants used in intracapsular cataract extractions.

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Results of intraocular lens implant surgery. The third Binkhorst medal lecture.

I compared an early series of 162 consecutive Copeland intraocular lens implants with a later series of 650 consecutive Binkhorst implants. Of the eyes with Copeland implants, 76.5% achieved 6/12 (20/40) or better visual acuity compared to 89.8% in the Binkhorst series. There was a striking difference in the incidence of clinically significant cystoid macular edema (less than 6/12 [20/40], visual acuity); 7.4% in the Copeland series and 1.4% in the Binkhorst series. I studied the Binkhorst series for visual acuity, causes of less than 6/12 (20/40) visual acuity, operative vitreous problems, additional surgery, secondary membranes, dislocations, and retinal detachment. A fluorescein angiographic study of 190 Binkhorst implants and 113 aphakic controls was done. There was a comparable incidence of cystoid macular edema in both groups at four, eight, and 16 to 24 months postoperatively. Extracapsular Binkhorst implants showed a lower incidence than intracapsular Binkhorst implants.

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A comparison of 500 Binkhorst implants with 500 routine intracapsular cataract extractions.

We compared 500 Binkhorst lens implants with 500 routine intracapsular cataract extractions. The two groups consisted of consecutive cases matched according to surgeons, surgical technique, time interval of the study, and ocular status. The results of visual acuity were comparable in the two groups; 89.0% of the implant group and 85.4% of the routine intracapsular group achieved 6/12 (20/40) or better visual acuity. The rate of complications in each group was comparable except in the case of corneal edema, which was higher in the implant group (1.2%) than in the routine intracapsular group (0.4%). The rate of clinically significant cystoid macular edema was higher in the routine intracapsular group (2.2%) than in the implant group (1.4%).

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Intraocular lenses: secondary membranes; cystoid macular edema.

In 650 consecutive Binkhorst lens implants, secondary membrane surgery was required more than eight times as frequently after an extracapsular than after an intracapsular cataract extraction. The visual acuity results after discussion were uniformly good. Transpars plana vitrectomy was reserved for more severe cases. The pupils were cleared, but the visual acuity results were mixed. A fluorescein angiographic study revealed little difference in the incidence of cystoid macular edema in implant and nonimplant cases. There was a lower incidence after extracapsular than intracapsular extractions in implant cases.

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Intraocular lenses--current status.

An attempt is made to depolarize current positions regarding intraocular implant lens surgery by presenting a reasonable list of advantages and disadvantages of the procedure. A current position on this controversial subject is presented and is based on currently available knowledge. Although this is a personal view, it is hoped that a middle ground can be created which would be acceptable to advocates and opponents of lens implant surgery.

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Pars plana vitrectomy for complications of intraocular lens implantation.

Several clinical situations have been presented in which pars plana vitrectomy has proven beneficial in the treatment of vitreous complications of lens implantation. Removal of the central opacity and enlargement of the pupil are essential to improve vision, relieve pupillary block and achieve an adequate view of the retina. Pars plana vitrectomy offers a method for the controlled removal of membrane, vitreous and iris tissues without unnecessary distortion of anterior segment anatomy.

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Lens implantation surgery in the second eye.

In a series of 730 patients who underwent lens implant surgery, 44 (6%) had bilateral implants. Eighty-eight percent of these patients had at least one year's interval between operations and 50% more than two years. Surgery on the first eye resulted in vision of 20/40 or better in 86% of patients. Eighty-three percent of patients were 20/40 or better in the second eye following surgery. The principal cause of vision less than 20/40 was senile macular degeneration. Follow-up observation ranged from 4-96 months. Conservative criteria are advised for bilateral implant surgery, with an appropriate interval between operations considering the increased complexity of the implant procedure.

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The iris-plane (Copeland) pseudophakos.

The iris-plane (Copeland) pseudophakos was evaluated in two 81-case surgical series. An early series consisted of the first 81 operations performed in the Miami community before a temporary moratorium on Oct 1, 1969. This series was compared with the first 81 operations performed after the moratorium was lifted on Oct 1, 1971. The follow-up period of those available for study was 63 months in the early series and 19 months in the later series. Objectivity was assured since all surgery was performed by one author (N.S.J.) and all examinations performed by the other author (L.R.D.). Visual acuity of 6/12 or better was obtained in approximately 80% of patients. The most frequent problems encountered were recurrent iritis and cystoid macular edema. The optic benefit was apparent in this elderly group of patients who avoided the optical problems of aphakia.

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