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Biomedical subjects

N Rupp

Publications and source records attributed to N Rupp.

At least 73 records · Page 4Linked to original sources
PubMed1983

The diagnostic value of morphology and relaxation times in NMR-imaging of the body.

NMR examinations were performed on a total of 109 patients using a resistive magnet. In 67 patients various organs and tissues of the face and neck the trunk and the limbs were evaluated in axial, sagittal and coronal planes. The use of more than one sequence time is essential for adequate representation of the anatomical structures and for detection and evaluation of pathological processes. They are the base to compute "secondary" T1- and T2-images, in order to obtain numerical values of both relaxation times. Thus a better understanding of the morphology of structures within the images is obtained. NMR appears to represent a sensitive method of tissue characterization: Specific changes in the T1- and the T2-pattern were found in pathological conditions, e.g. longer T1-times with normal or moderately longer T2-times in tumors compared to healthy tissue and extremely long T1- and T2-times typical of fluid accumulations.

Abdomen↗
PubMed1982

[Head and neck cancers. What's new in clinical oncology for the practicing ENT physician?].

An interdisciplinary evaluation is made of the most common forms of head and neck cancer, with emphasis on certain aspects.--In the field of x-ray diagnostics, computed tomography dominates varying importance being given to the individual organs. Nuclear medicine pays particular attention to skeletal scintigraphy and gallium scintigraphy. In radiation therapy, progress has been made especially through the use of optimal radiation planning as well as the use of the after-loading technique and neutron radiation. Antineoplastic chemotherapy is currently being used as palliative treatment, adjuvant chemotherapy and as the first step towards a curative therapy.

Antineoplastic Agents↗
PubMed1981

[Therapeutic embolization by angiographic catheter (author's transl)].

Vascular occlusion can be performed by remote-controlled, fluoroscopically guided angiographic catheters and selective injection of occlusive material. Inoperable tumors, acute bleeding, organ devitalization, and vascular malformations can be indications for this method. In difficult operation sites, this could be the preferred as definitive treatment. As a preoperative procedure, it can help control intraoperative hemostasis and thus shorten the operation time. During the last few years the most frequent indications in our department were acute bleeding and vascular malformations.

Angiography↗
PubMed1981

Percutaneous biopsy of retroperitoneal lymph nodes. A multicentric study.

Percutaneous transperitoneal biopsy of retroperitoneal lymph nodes is a fast and well tolerated procedure to improve the diagnosis of metastasis for staging primary tumours and general lymphatic disease. In 303 patients examined by lymphography and biopsy, cytology disclosed metastases in almost twice as many patients as lymphography alone. By combining both examinations, staging operations can be omitted in many patients.

Adult↗
PubMed1981

Evaluation of the cruciate ligaments by CT.

Delineation of the cruciate ligaments in 112 patients using the computed tomography under arthrographic conditions was reported. Special position were used allowing for the demonstration of both cruciate ligaments in their complete lengths. In 6.2% of the examinations a reliable demonstration of the cruciates was not possible for technical reasons. Demonstration of normal cruciate ligaments in CT arthrography was described and normal values were tabulated. Recent cruciate ligament injuries were seldom examined by CT arthrography since the clinical symptoms were mostly unequivocal. The old ruptures of the ACL were divided into 4 different types: Type I: Rupture of the femoral origin that adjoins the PCL. Type II: Attenuation of the intraligamentary ruptured ligament with a preservation of origin and insertion. Type III: Complete rupture with shrinking and retraction of the fragments. Type IV: Osseous involvement of the femoral origin or tibial insertion. In 36 old cruciate ligament ruptures, the sensitivity of this method of investigation was 97%, the specificity 100%. After reconstructive surgery, CT arthrography allows for an objective analysis of the operative results and permits the comparison of different techniques of surgical repair.

Humans↗
PubMed1980

[The clinical importance of arthrography after lesions of the meniscus and capsular ligament (author's transl)].

Clinical, arthrographic and operative findings of 100 patients were compared and analyzed by a study group with the result, that in questionable lesions of the meniscus, the indication for a double contrast arthrography was markedly reduced when plain films of the knee, an exact case history and a physical examination of the knee joint were performed. Above all, the improved examination technique, with the knowledge of the functional anatomy of the capsular ligament apparatus and the correlation of all stabilizing forces of the knee joint had reduced clinical errors in diagnosis. Clinically clearly analyzed meniscus lesions are therefore no indication for arthrography. In our clinic the indicatin will be reduced to those cases where there are still complaints after meniscectomy. There is a great advantage, if the examinating physician, the radiologist and the orthopedic surgeon cooperate closely together.

Hot Temperature↗
PubMed1980

[The demonstration of the cruciate ligaments by xerotomography (author's transl)].

Demonstration of the cruciate ligaments by xerotomography was attempted in 54 patients after double contrast arthrography of the menisci. The best results of lateral tomography were achieved in showing the middle and caudal portions of the anterior ligament. The ligaments close to the femur are not well demonstrated. Twenty-six patients underwent operation; of these, 13 had ruptured cruciate ligaments. The correct diagnosis was made by xerotomography in only 46%. The reasons for this are discussed. The present results do not suggest that Xerotomography is valuable in the diagnosis of abnormalities of the cruciate ligaments.

Evaluation Studies as Topic↗
PubMed1980

[CT for staging of systemic lymphatic diseases (author's transl)].

In 75 patients with lymphoma (46 Hodgkin's disease, 29 non-Hodgkin lymphomas) computed tomography was performed in order to detect neoplastic invasion of the abdominal organs (55 new cases) or to control the results of treatment (20 cases). In 30 cases enlarged retroperitoneal or mesenteric lymphnodes and/or liver or spleen enlargement were found. Neoplastic involvement of lymphnodes without enlargement was missed in two cases. CT failed also to demonstrate microscopic malignant invasion of liver and spleen. The false-negative rate in our series was 10.9%. Computed tomography is a non-invasive method which is very well suited for staging malignant lymphoma.

Hepatomegaly↗
PubMed1980

[Percutaneously introduced bile duct prostheses as primary measure in obstructive jaundice (author's transl)].

The simplest measure for overcoming obstructive jaundice, and the one with the least complications, is percutaneous transhepatic bile duct drainage, which we have carried out on 38 patients. We have abandoned the catheter technique with combined external and internal drainage and instead use primary implantation of a bile duct prosthesis by the transhepatic route in cases of obstructive jaundice. The results are better, and the procedure is easier for the patient. Our experience with twelve implants in nine patients is described.

Adult↗
PubMed1980

[CT and lymphography correlations in the evaluation of patients with testicular tumours (author's transl)].

27 patients with testicular tumours were examined by lymphography and computerized tomography for evaluation of metastatic spread in the retroperitoneal lymphnodes. A good correlation of results was found in 23 patients. In 4 cases lymphography failed to show metastatic disease, which was easily recognized by CT. In account of the lymphatic spread pathways of testicular tumours leading mainly to the lymphnodes close to the kidney pedicle CT appears to be method of choice in the staging of these patients, as the lymphnodes in this area are often not demonstrated by lymphography. Computerized tomography allows the exact localisation and extension of neoplastic lymphnodes and at the same time a good evaluation of the surrounding organs.

Dysgerminoma↗
PubMed1979

[Transperitoneal fine needle biopsy of retroperitoneal lymph nodes in cancer diagnosis].

Preoperative lymphography was performed in 97 patients with urological malignoma. Fine needle punctions were performed of 458 suspicious as well as non-suspecious lymph nodes. In 22 cases lymphographic and cytological findings were compared with histological results after lymphadenectomy. It could be shown that of 15 cases with lymph node metastases lymphographic and cytologic findings were corresponding in 6 cases. In 9 cases tumor cells were found in lymph nodes even though the lymphogram was rated non-suspicious. It is concluded that fine needle biopsy of lymph nodes after lymphography is an important improvement in preoperative diagnosis of malignoma.

Adenocarcinoma↗
PubMed1979

[Value and results of computer tomography in diseases of the pancreas (author's transl)].

In a joint study carried out by the radiological university clinics of Bonn, Hamburg, Cologne, Leuven and Munich, 483 computer tomographs of the pancreas were evaluated. A correct histological diagnosis, or one confirmed at surgery, was obtained in 74.5% of 168 cases; in a further 9% an abnormality was seen in the pancreas or in its immediate vicinity, but was wrongly interpreted. The computer tomographic criteria of inflammatory processes and of tumours of the pancreas are given, and the not uncommon difficulties in distinguishing between these are discussed.

Acute Disease↗
PubMed1979

[Algorithms in the radiological diagnosis of malignant disease (author's transl)].

Algorithms in the diagnosis of malignant disease have the aim to produce a diagnosis as quickly, as certainly and as simply as possible. The first phase consists of general non-invasive methods which should be as simple as possible. If the results are positive this should be followed immediately by percutaneous biopsy in order to produce cytological confirmation of the diagnosis as quickly as possible. If the original investigations were negative, those special methods of investigation should be used which are most likely to make a diagnosis. This is followed by investigations which throw light on the most appropriate form of treatment. This scheme has been illustrated by special algorithms for carcinoma of the bronchus, the pancreas and the breast.

Breast Neoplasms↗
PubMed1979

[Percutaneous transhepatic bile duct drainage for obstructive jaundice (author's transl)].

Palliative percutaneous bile duct drainage was carried out in five patients with obstructive jaundice due to inoperable tumours. In four patients drainage was continued for a long period, in one patient for only one day. The bile duct was punctured by transhepatic cholangiography. It was then catheterised and a drainage catheter introduced into the duodenum in order to produce both internal and external drainage. This procedure, which carries few complications, produces a rapid reduction of jaundice and disappearance of pruritus. It does not increase the expectation of life, which depends on the underlying disease. Experience with this method may be of value in benign stenoses or in pre-operative drainage.

Bile Ducts, Intrahepatic↗