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Biomedical subjects

N Rodríguez

Publications and source records attributed to N Rodríguez.

At least 19 recordsLinked to original sources
PubMed1989

[Immediate and 1-year survival after cardiopulmonary resuscitation at an intensive care unit].

Eighty consecutive patients requiring cardiopulmonary resuscitation (CPR) for cardiorespiratory arrest (CRA) were prospectively studied. The immediate survival rate and the survival rates after 48 hours, at the time of hospital discharge and one year later were evaluated. Forty-one patients (51%) initially recovered from CRA, 20 died in the hospital and 17 (21% of the initial group) survived after one year. Survival was related to: 1) the mechanism of CRA. Ventricular tachycardia-fibrillation (VT-VF) had a better prognosis than asystole (AS) and electromechanical dissociation (EMD) (p less than 0.005). 2) Duration of CPR. The survival was higher when CPR lasted for less than 15 minutes (p less than 0.001). 3) Underlying disease. The classification of the patients in three categories depending on the underlying condition permitted an approach to the prognosis of CPR. Group A: patients who did not benefit from CPR, without survivors at the time of hospital discharge. Group B: patients who had a benefit from CPR, with a 37% survival at the time of hospital discharge and 33% after one year, with a good quality of life and a good neurological status. Group C: patients in whom the benefit of CPR was variable, with a similar survival rate as group B at the time of discharge, but with a reduction to 20% in the subsequent year.

Adolescent↗
PubMed1989

[Preliminary experience in fetal blood obtainment through cord punction].

Seven umbilical cord punctures where done in viable fetuses. The procedure was successful in all cases, the fetuses had anomalies or non immune hydrops fetalis. There was one case in which the indication was autoimmune thrombocytopenic purpura. There is high risk in the punction, but the prenatal diagnostic studies is necessary and useful. The authors comment advantages and complications in this procedure.

Anencephaly↗
PubMed1989

[Doppler in 42 high risk pregnancies: predictive values of the flow velocity wave indexes in the arcuate and umbilical arteries].

Doppler exams were done in forty two risk pregnancy. We explored arcuate and umbilical arteries in order to determine the predictive values of different index in flows velocity wares. Method sensibility was 83.33% y 100% in arcuate and umbilical arteries respectively. Specificity was 100% and 94.9% predictive value of negative test was 97.24 y 100% in both arteries. Predictive value of positive test was 100% and 71.42% in both arteries. The results are very similar to others scientific reports in the same subject.

Adult↗
PubMed1989

[Prediction of fetal sex by ultrasonography].

Five hundred thirteen echographic reports are analyzed in order to predict fetal sex between 17 and 39 weeks of pregnancy. The diagnostic certainty was of 98.06%. The error was of 1.48% for masculine sex and 2.49% for feminine sex. Podalic presentation and early and late pregnancy influenced negatively in the prediction of the fetal sex. The amniotic fluid, placental localization, and any abnormality of the fetal anatomy, have no influence in the prediction of the sex. The best moment for sex prediction was between 28 and 36 weeks of pregnancy.

Female↗
PubMed1988

The interaction of homologous series of alkanols with sodium channels in nerve membrane vesicles.

The potency of members of the homologous series of alkanols to block 22Na uptake through sodium channels stimulated by veratridine was studied in membrane vesicles obtained from lobster walking leg nerves. A cut-off was revealed at the level of 1-undecanol. However, secondary isomers of inactive primary homologues, such as 5-dodecanol and 5-tridecanol, were able to block ion flux. From the concentration required for an equipotent effect, it was calculated that the standard free energy for adsorption of primary alkanols is -725 cal/mol CH2. Furthermore, since the concentration required for an equipotent effect for primary isomer was found to be lower than that obtained for secondary isomers, it is concluded that the latter are less potent than the former. The similarity between this set of results and those obtained in intact frog sciatic nerve (J. Requena et al., J. Membrane Biol., 84:229-238, 1985) offers further support to the notion that the procedure employed to isolate the membrane vesicles does preserve the Na channels. However, the mechanism of alcohol inhibition of the Na channel in isolated membrane vesicles would seem to be somewhat different from that preferred in axons. While in vesicles the block needs to be thought in terms of a reduction in the number of conducting Na channel, in axons this is considered to be the less likely mode of action, mainly because under veratridine it is not possible to invoke a shift in the steady-state activation or inactivation.

Alcohols↗
PubMed1987

Effect of ascorbic acid on the hepatotoxicity due to the daily intake of nitrate, nitrite and dimethylamine.

It is known that nitrates, nitrites and dimethylamine may react in the gastro-intestinal tract synthesizing the powerful hepatotoxic and carcinogenic dimethylnitrosamine. The purpose of this study was to investigate hepatotoxicity due to the daily intake of nitrates and nitrites administered to rats during 14 weeks together with dimethylamine in drinking water, and to evaluate the protecting effect of ascorbic acid against the hepatotoxicity of the presumably endogenous formed dimethylnitrosamine. The toxicity criteria studied were weight of liver (absolute and relative), free and total bilirubin, alkaline phosphatase and pyruvic glutamic transaminase, all in the form of serum, and histopathologic tests of the liver. The results gave evidence of hepatotoxicity induced by the intake of nitrate, nitrite and dimethylamine all together, and not through the only intake of nitrate or nitrite or of amine. Daily doses of ascorbic acid [(211 +/- 40) and (18 +/- 4) mg/kg] seemed to hinder hepatotoxicity according to the criteria under investigation.

Alanine Transaminase↗
PubMed1986

The localization of a lectin-like component on the Leishmania cell surface.

The binding between macrophage-like cells J774G8 and Leishmania braziliensis (NR) promastigotes was studied 'in vitro' by a radioisotopic assay under various conditions in the absence of serum. Different sugars, N-acetyl-D-glucosamine, D-glucose, D-mannose, D-galactose, and chitin, diminished the binding of the parasite, whereas other sugars, D-arabinose, D-fucose and D-xylose, did not affect the binding. The presence of a lectin-like ligand specific for N-acetyl-D-glucosamine has been detected on the cell surface of the Leishmania braziliensis (NR) by fluorescence microscopy. These data suggest that the binding of the parasite to the host's cell is a ligand-receptor interaction which involves the participation of a lectin-like component on the parasite cell surface.

Animals↗
PubMed1978

[Laparoscopy].

Explore the source record for details and available documents.

Adult↗