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Biomedical subjects

N Robertson

Publications and source records attributed to N Robertson.

61 records · Page 4Linked to original sources

Aortic regurgitation and mitral valve prolapse with Down's syndrome: a case-control study.

This case-control study was designed to determine whether aortic regurgitation (AR) and mitral valve prolapse (MVP) are specifically associated with Down's syndrome, or occur in a comparably retarded population without Down's syndrome. The 92 control subjects resided at the same institution as the 131 cases, and had mental retardation attributable to low birth weight or perinatal asphyxia. Mean (+/- SD) ages of the cases and the control group were 41 +/- 11 years compared with 40 +/- 13 years, respectively. The relative risk of AR among the cases (those with Down's syndrome) was 2.9 (95% confidence interval, 0.65-13.2; P = 0.16) and that of MVP was 3.5 (95% confidence interval, 1.2-10.2; P = 0.02). The results showed that these two valvular abnormalities are specifically associated with Down's syndrome in adults.

Adult↗

Job satisfaction of HMO pharmacy personnel.

This study identifies and examines the job satisfaction of pharmacy personnel in a large integrated prepaid group practice HMO. A large share of pharmacy personnel were satisfied with almost all aspects of their jobs. There were few differences between pharmacists and support personnel in satisfaction with specific aspects of their jobs. Among pharmacists, the challenge of their work, their management, and their physical working environment were the most significant factors in their overall job satisfaction while among support personnel the control of their work was the only significant factor. It seems that working in a large HMO can be satisfying for pharmacy personnel.

Health Maintenance Organizations↗

Self-reported burnout among HMO pharmacists.

This study examines self-reported burnout, potential risk factors and causes, and self-reported solutions to burnout among different types of pharmacists in a large prepaid group practice HMO. A substantial share of pharmacists reported that burnout is or has been a problem with them. The quality of the job was mentioned as the most frequent cause of burnout by all types of pharmacists. More variety and responsibility and decreased workloads were the most frequently offered solutions to burnout by both staff and supervisor/specialist pharmacists. The findings suggest that pharmacists' burnout should be of concern to management.

Attitude of Health Personnel↗

Valvular heart disease (aortic regurgitation and mitral valve prolapse) among institutionalized adults with Down's syndrome.

Congenital heart disease has long been recognized in children with Down's syndrome, but little is known about the manifestations of clinical heart disease in adults with this condition. Therefore, 131 adults with Down's syndrome were examined. Clinical heart disease was considered to be present when an abnormally split S2, systolic click, at least grade 3/6 systolic precordial murmur, or any diastolic precordial murmur was heard. Using these criteria, 38 patients had clinical heart disease and 93 did not. To confirm and evaluate the auscultatory findings, echocardiograms were recorded in 37 of the patients. Comparison between patients without clinical heart disease and those with clinical heart disease showed that neither age (39 +/- 11 vs 40 +/- 12 years, respectively) nor gender (60% vs 66% men, respectively) differed significantly. Eleven had clinical and echocardiographic findings consistent with atrial or ventricular septal defect. Findings consistent with aortic regurgitation were identified in 8, and 18 had mitral valve prolapse. These results suggest that in addition to atrial and ventricular septal defect (which have a well recognized association with Down's syndrome), 2 specific, usually asymptomatic, and heretofore unanticipated valvular cardiac abnormalities may be associated with Down's syndrome.

Adolescent↗

The changes produced by presurgical orthopedic treatment of bilateral cleft lip and palate.

A serial cephalometric analysis (with the aid of metallic implants) and an analysis of the models of 10 children with complete bilateral clefts, who received presurgical orthopedic treatment, was done. It revealed that such therapy can successfully reduce the protrusive deformity of the premaxilla, when forward growth of this structure is restrained so as to allow the remainder of the face to "catch up." Our other observations include the accentuation of the columella during treatment, but an absence of growth at the cleft margins. Orthopedic treatment which fails to achieve the desired aims in 12 weeks of active therapy should be discontinued then in favor of such surgical setback as may be necessary to allow a satisfactory lip repair.

Cephalometry↗

The impact of the docent clinical pharmacist on treatment of streptococcal pneumonia.

This two-phase retrospective study was designed to evaluate the impact of the clinical pharmacist on prescribing practice of physicians in an internal medicine service. Streptococcal (pneumococcal) pneumonia was chosen as the model disease state. The drug of choice was used more frequently and there was a statistically significant difference in raw cost of antibiotic, total cost for antibiotic administration, daily raw cost for antibiotics; total raw cost for antibiotic administration, and patient charges when physicians were exposed to the clinical pharmacists' influence.

Anti-Bacterial Agents↗