After prolonged occupation exposure to amorphous silica dust-a product of vaporized crystalline silica (quartz)-eleven out of forty workers showed reticular and/or nodular abnormalities in roentgenograms of the chest. From this group, we present three illustrative cases. These had widespread pulmonary disease with granulomatous nodules and fibrosis (documented histologically in two cases), but there was no demonstrable restrictive impairment of pulmonary function. We discuss the possible importance of this previously underestimated toxicity, especially in an industrial setting.

Dust↗

PubMedDate not supplied

Retrograde pancreatic venography after reduction of the arterial visceral flow: an experimental study.

To evaluate techniques for retrograde pancreatic venography similar to epinephrine renal venography, 35 dogs had transjugular portography before and after the infusion of various doses of vasopressin systemically or selectively into the superior mesenteric and celiac arteries, or after occlusion of the distal thoracic aorta. Increased filling of the peripheral portal branches resulted, but none of the techniques provided diagnostically useful enhanced pancreatic visualization.

Animals↗

PubMedDate not supplied

The combination of adenosine-triphosphatase inhibition and provision of high-energy phosphates for the preservation of unperfused myocardium, assessed by ventricular function, histochemistry and birefringence.

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Adenosine Monophosphate↗

PubMedDate not supplied

Assessment of the heart by histochemical and birefringence techniques as compared with ventricular function tests.

We have compared results of isovolumic ventricular function studies and results of histochemical and birefringence examinations of biopsy specimens from 80 isolated canine hearts both before and after three hours of preservation utilizing several variables. The direct and derived mechanical tests and histochemical and birefringence assessments of the myocardium were correlated by multiple regression analysis. Our results suggest that initial ventricular health may be indicated by acid hematein staining of free phospholipids and by the response of myocardial birefringence to adenosine triphosphate and calcium, while succinic dehydrogenase staining and birefringence without adenosine-triphosphate treatment are more useful in showing ventricular deterioration during operation.

Animals↗