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Biomedical subjects

N Pandiyan

Publications and source records attributed to N Pandiyan.

9 recordsLinked to original sources
PubMed2000

Medical management of male infertility.

The medical management of male infertility has a precise role to play. Inappropriate use of drugs, apart from not promoting fertility, may actually predispose to infertility. Gonadotoxic or gametotoxic drugs should be avoided if possible. If potentially toxic drugs are used for a medical condition, suitable, less or non-toxic alternatives should be used. Where medical management is not possible, instead of wasting time and money on expensive unproven therapies, early recourse to assisted reproduction must be sought.

Journal Article↗
PubMed1996

Mitotic chromosomal anomalies among 1210 infertile men.

Detailed medical and clinical examinations were carried out on 1608 men attending an infertility clinic to determine if any of those exhibiting abnormal semenograms also had any other readily identifiable clinical condition. In all, 1210 men showed abnormal semenograms according to World Health Organization criteria. Karyotyping of the white blood cells in these 1210 men revealed 44 (3.6%) individuals with either autosomal or sex chromosomal aberrations. However, no single characteristic feature of their semenogram or clinical condition was of any diagnostic value to predict the existence of a chromosomal anomaly.

Chromosome Aberrations↗
PubMed1988

Postmolar contraception.

Recent studies on the etiology and the cytogenetics of trophoblastic tumors suggest that hydatidiform mole and choriocarcinoma may be conditions with no causal relationship. With the advent of newer diagnostic methods which aid in the early diagnosis of pregnancy and help to differentiate it from abnormal pregnancy together with the increasing concern over the safety of use of the contraceptive measures following a hydatidiform mole, it is suggested that a period of postmolar contraception may no longer be necessary. The follow-up of these patients should include serial sonography in association with other currently available methods. Pregnancy should also be allowed to occur naturally if the patient so desires.

Contraception↗
PubMedDate not supplied

Management of dysfunctional uterine bleeding.

DUB is a common symptom which is mainly due to disorders of ovulation and local endometrial dysfunction. The diagnosis should be made only after excluding organic pelvic disease. Anaemia and other endocrine and systemic causes of DUB must be treated promptly. Spontaneous cure is also possible. However, in patients in whom the symptoms persist, drug treatment with combined oestrogen-progestogen, anti-prostaglandin and anti-fibrinolytic agents is often effective. Hysterectomy and hysteroscopic endometrial ablation are contemplated only in persistent DUB in older and parous women and radiotherapy has no place amongst the modern modalities of management.

Age Factors↗