Biomedical subjects
Publications and source records attributed to N Nedopil.
Ten chronic schizophrenic patients were treated with hemoperfusion on a weekly or twice weekly basis for 6 to 10 weeks. Two of the patients improved markedly, while the condition of three of them deteriorated. These findings indicate that this method might not be of general usefulness in the treatment of chronic schizophrenic patients.
In an open pilot study, 9 schizophrenic patients were treated with the synthetic analogue of methionin-enkephalin FK 33-824 on two consecutive days in a dose of 0.5 mg on the first day, and 1.0 mg on the second day (infusion for 2 hours). 3 patients refused therapy during or after the first infusion; of the remaining 6 patients (2 hebephrenic, 4 paranoid type) 5 patients improved remarkably on the first and second day. The total BPRS-score and 4 of the 5 factors of the BPRS-scale were reduced significantly the day after treatment compared to pretreatment values. The improvement continued for 28-168 hours.
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The FPDS is an extension of the AMDP-System to forensic psychiatry which comprises four sections (The files--The AMDP System--Complementary anamnestic and clinical data--Medicolegal data). Its completion takes 40 to 60 min. Its first application to medicolegal reports is described and its perspectives outlined.