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Biomedical subjects

N N Golokhvastov

Publications and source records attributed to N N Golokhvastov.

7 recordsLinked to original sources

[Topical diagnostic methods in primary hyperparathyroidism].

The efficiency of USI of the neck, scintigraphy of the parathyroid glands (PTG) with selen-methionine and selective catheterization of veins (SCV) of the neck and mediastinum for preoperative determination of the localization of the source of hyperproduction of the parathyroid hormone was analyzed on the basis of results of examination of 149 patients including 51 patients with primary hyperparathyroidism confirmed during the operation. It was noted that none of the methods of topical diagnostics used in the work is thought to be universal for different clinical situations. A method of their complex use is proposed which foresee USI of the neck as the first step. In case of insufficient information of the results of USI the authors propose SCV of the neck and mediastinum as a method of choice which allows the size and level of the altered PTG to become more exact and which makes further search with the help of other methods of topical diagnostics more purposeful and effective.

Adolescent↗

[Hemodynamics and gas exchange in experimental pulmonary microembolism].

Parameters of hemodynamics and gas exchange were studied in experiments in 25 dogs having experimental microembolism of the lungs. Microembolism was found to result in an abrupt increase of the pulmonary arterial pressure and resistance of lungs, stable hypoxemia with phenomena of metabolic acidosis, incrsed intrapulmonary shunting and the ventilation/perfusion ratio. The mechanisms of hemodynamic and respiratory rearrangement are discussed.

Animals↗

[Evaluation of the amount of microaggregates in preserved blood].

The tensometric method of the estimation of microaggregates in the blood and its preparations was used. It was shown that the process of aggregation of blood formed elements was dependent on the preservative content, period of storage and individual features of the donor. The filtration rate of the soviet and foreign microfilters was found to depend upon the initial content of microaggregates in the blood. The employed tensometric method is sufficiently simple and enables the objective estimation of the amount of microaggregates to be made. It is recommended for employment in the blood transfusion service.

Blood Cell Count↗

[Changes in vascular permeability and lymph outflow during blood transfusions: experimental study].

Experiments on mongrel dogs showed that after transfusion of citrated blood the lymph flow in the thoracic and right lymphatic ducts increased. Greater vascular permiability and accumulation of fluid in the lungs were also noted. The degree of these phenomena was dependent on the time of storage of the transfused blood and on getting thrombo-leukocytic microaggregates into the vascular bed. The question of possible sequellae of hemotransfusions in patients with the incompetent lymphatic system is discussed.

Animals↗

[Tensometric analyser for blood microaggregates].

A tensometric analyser based on blood pressure determination on a screen-like filter is recommended to estimate the quantity of microaggregates being formed in the blood. This instrument has small dimensions and consists of a measuring chamber, automatic syringe and a device for thermostating and control purposes.

Blood Pressure↗