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Biomedical subjects

N N Bragina

Publications and source records attributed to N N Bragina.

At least 19 recordsLinked to original sources
PubMed1999

[The psychopathology of tumors of the 3rd cerebral ventricle].

36 patients with tumors of diencephalic region of different histologic nature involving cavity of the third ventricle of the brain were observed. 27.7% of the patients had disorders of mental and physical development from the very first years of life. In presurgical period there was a wide spectrum of paroxysmal and permanent mental disorders from asthenia to rude disturbances of memory and consciousness which regressed or disappeared after the operation. The correlation was observed between such disorders, histologic structure and location of the tumor; individual characteristics of the patient (age, dextrality, sinistrality); scope and character of the operation (approach to the tumor, surgical interventions on the structures of the third ventricle).

Adolescent↗
PubMed1998

[Central regulatory disorders in the clinical picture of the early postoperative period in patients with tumors of the midbrain].

Neurological, clinical, biochemical examinations, electroencephalography, computer and magnetic resonance tomography of the brain of 336 patients with brain stem and para-brain stem tumors resulted in conclusion that nonspecific autonomic-endocrine reaction caused by disorders in central regulation was the main component of early postoperative period. The first type of such disorders included cases with rather stable indices of both hemodynamics and ionic-osmotic homeostasis characterized by favourable course. Unstable hemodynamics and tendency to increase of osmolarity and serum levels of sodium and glucose as well as unfavourable course of this period were typical for the second type.

Adolescent↗
PubMed1997

[The early postoperative period in patients with tumors of the posterior cranial fossa].

The studies carried out during an early postoperative period in patients with posterior fossa tumors were made to analyse the role of the degree and the level of brain stem damages in formation of cerebral reactions. The three groups of cases were selected in accordance with the course of the postoperative period: 1.1-with exitus letalis (irreversible damages); 1.2-rehabilitation in persistent focal damages; 2-restoration with functional safety of brain stem. Differences of the integral cerebral reactions (the state of consciousness, emotional-affective disorders, awakening state) as well as the brain stem syndromes (formation of pathological systems, reciprocal relations between intact and destroyed brain stem structures) and diencephalic-subcortical syndromes were considered.

Adult↗
PubMed1997

[Clinical picture of colloid cysts of the III ventricle].

Clinical analysis of 74 cases of colloid cysts of the III-d ventricle was performed. Dynamics of clinical symptom complex was studied both in preoperative and early postoperative period as well as in remote periods after surgery. Most of the patients were treated in N.N. Burdenko Institute of Neurosurgery during 1980-1995. Peculiarities of the disease development before clinical manifestation, variations of complicated postoperative period, prognostically significant symptoms, possible mechanisms of clinical syndromes development were considered.

Adolescent↗
PubMed1993

[The characteristics of epilepsy in left-handed people (a clinico-electroencephalographic study)].

As many as 16 epileptic patients with the sings of sinistrality in the motor and sensory spheres were examined. The authors demonstrate the clinical characteristics of epilepsy in the left handed, that distinguish them from the right-handed; dissimilarity of each psychopathological symptom and syndrome to their analogs in the right-handed, the occurrence of unusual phenomena, impossible in the right-handed. Depict specific features of the EEG that distinguish the patients examined from healthy right- and left-handed. The data obtained are interpreted as evidence that the clinical characteristics and the EEG appearance of epilepsy are determined to a considerable measure by the profile of asymmetry of each patient as well as by the fact that the left-handed may demonstrate diverse varieties of functional brain asymmetry, differing from the type of asymmetry of cerebral hemisphere functions common to all the right-handed in the maintenance of integral neuropsychic activity.

Adolescent↗
PubMed1991

[Diagnosis of intracranial hypertension in patients with severe cranio-cerebral trauma].

Manifestations of brain injury were examined in 64 patients with severe craniocerebral injuries on the basis of comparing the clinico-neurological data to the results of continuous long-term control of intracranial pressure (ICP) and computer-aided tomography (CT). As a rule, patients with well-defined focal cortico-subcortical symptomatology demonstrated normal ICP, with no ventricles and cisternae of the basis cerebri being compressed as shown by CT. In patients with the increasing brain stem symptoms associated with the levelling of the focal cortico-subcortical symptomatology, ICP was elevated and computer-aided tomograms showed foci of brain contusion, intracranial hematomas, compressed ventricles and cisternae of the basis cerebri. If gross symptoms of the derangement of the basis cerebri appear in the foreground with no focal cortico-subcortical lesions being manifest, the patients develop, as a rule, stable and increasing hypertension while CT shows the signs of gross compression of the ventricles and cisternae of the basis cerebri in conjunction with foci of brain contusion and intracranial hematomas. In primarily unilateral hemispheric lesions, the patients manifest asymmetric hydrocephalus.

Brain Injuries↗
PubMed1988

[Korsakoff's syndrome in the clinical picture of craniocerebral injury].

The localization and the nature of brain lesions are among the most debatable issues in Korsakoff's syndrome (KS). In 28 patients with head trauma the neurological investigation and CT scans helped to distinguish between the following stages of KS progress and reversal: (1) whole brain response with consciousness deterioration and psychomotor excitement; (2) predominantly focal involvement of the right hemisphere; (3) regression of KS clinical manifestations.

Adolescent↗
PubMed1987

[Use of L-DOPA in the complex treatment of severe craniocerebral injuries].

The article is based on an analysis of the results of clinicobiochemical study of 15 patients with severe craniocerebral trauma (SCCT) whose intensive multiple-modality treatment included the use of L-DOPA. All the patients presented with direct traumatic lesions of the subcortical structures attended by diminished excretion of dopamine and DOPA. A favourable clinical effect was related to the use of DOPA which indicates that it is advisable that the drug be included into the combined therapy of severe injury to the brain attended by dysfunction of the subcortical formations.

Adolescent↗
PubMed1985

[Recovery of consciousness after prolonged coma in patients with severe craniocerebral injuries].

The authors specify and describe 7 stages of regaining consciousness by patients who had been in coma from 11 to 180 days, including opening of the eyes; fixation of the eyes on an object; recognition of close relatives; understanding of directly addressed speech; patient's own speech; amnestic confusion; consciousness with all formal signs of being clear. The condition of the patients at these stages is compared with EEG findings suggestive of the functional disintegration of the brain as a system in comatose patients, the vegetative status and the restoration of connections between different departments of the brain corresponding to the recovery of long absent consciousness of patients. It is concluded that at the current stage of medical sciences the maximum duration of coma compatible with the subsequent full recovery of mental activity of the patient under 30 years does not exceed 11 days.

Adolescent↗
PubMed1977

[Clinical features of focal brain lesions in the left-handed and ambidextrous].

On the basis of a study of 31 patients who demonstrated deviations from dextrality (Simistrals and ambidextrals) the authors describe some traits of the nervous and mental changes in focal brain lesions. There are insignificant correlations between the character of nervous and mental changes and the side of a brain lesion. The study demonstrated a wide variability of the clinical symptomatology, a peculiarity of each neurological and psychopathological phenomenon, distinguishing them from similar changes in dextrals. The studied contingent revealed prevalence of a disturbed sensory cognition in the clinical picture; the presence of special phenomena which most likely are not seen in dextrals and which are also related to a pathology of sensory cognition. It is being assumed that these clinical traits may testify to an insufficiency of speech lateralization in sinistrals and that an insufficient speech lateralization is accompanied by other than in dextrals organization of sensory processes.

Brain Diseases↗
PubMed1975

[Consciousness disorders in focal lesions of the right and left cerebral hemispheres].

In the light of modern concepts of functional asymmetry in the human brain, the authors analyse paroxysmal conditions of changed consciousness which occurred in 160 patients with lesions of the hemispheres due to brain tumors (75 patients) and in epilepsy (85 patients). It is shown that certain forms of changed consciousness are characteristic of disorders of the right and left hemispheres in right-handedness. This clinical fact is taken as a basis for the assumption that in the formation of consciousness both hemispheres in different ways play a certain role and they provide different "formating" kinds of consciousness: the right hemisphere--a direct perception or a sensory perception of the environment and itself, the left--process of abstract perception based on speech, symbols, semantics.

Brain Neoplasms↗