Screening for ovarian cancer.
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Biomedical subjects
Publications and source records attributed to N Manassiev.
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Hysterectomy is one of the most common gynaecological surgical operations performed in the UK. In addition to causing the early onset of the menopause, hysterectomy can lead some women to be at increased risk of future CHD and osteoporosis owing to declining oestrogen levels. Hysterectomised women are therefore an ideal group to receive hormone replacement therapy (HRT). However, only small numbers of women receive HRT owing to a number of factors, including fear of potential complications and adverse side-effects. Of those women who do receive HRT, compliance with therapy is low. In this article, the authors weigh the benefits of HRT, in terms of relief of menopausal symptoms, and prevention of osteoporosis, Alzheimer's disease and cardiovascular disease, against the known risks. The authors suggest that compliance with HRT could be optimised by profiling patients in general practice and by educating women on the long-term benefits of HRT.
There is controversy about the value of continuous versus intermittent auscultation of the fetal heart during labour, but there is no agreement on what constitutes normal heart rate of a term fetus. There are variations between the definitions adopted by different countries, and even within a single country. We propose 110-160 beats per minute for clinical use.
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