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Biomedical subjects

N M Newman

Publications and source records attributed to N M Newman.

At least 55 records · Page 3Linked to original sources
PubMed1984

Adolescent pregnancy in Tasmania.

The obstetric performance of 1719 pregnancies in mothers aged less than 18 years was compared to that of the rest of the obstetric population. There was a significantly poorer outcome in the adolescents in the mean birthweight, the prevalence of birthweight below 2500 g and of gestation period below 28 weeks, Apgar score, perinatal mortality and the occurrence of hypertension in pregnancy. When the primiparous adolescent group (1607) was compared with primiparas aged 18-34 years (16 220), these differences were less marked. The two groups (adolescent and adult primiparas) were matched by marital status and socioeconomic class, and no significant differences were found in these parameters. It is concluded that biological age per se does not confer an increased risk in pregnancy. The high proportion of primiparas in the adolescent group (93%), and the associated increased prevalence of high-risk factors in this group (single marital status, low socioeconomic class, and smoking) would explain the poorer obstetric outcome in comparison with that of the total adult group.

Adolescent↗
PubMed1984

Debendox withdrawn.

Explore the source record for details and available documents.

Abnormalities, Drug-Induced↗
PubMed1984

A case of "trigger toe".

"Triggering" of the toes, in which local tendon hypertrophy prevents the smooth movement of the tendon, has been described as a problem more theoretical than real and only three cases have been reported. The authors report a case of partial tethering of the flexor hallucis longus tendon just distal to the medial malleolus in a 28-year-old jogger who had painful triggering of the great toe on plantar flexion of the ankle and great toe. Division of the flexor hallucis longus tendon pulley distal and posterior to the medial malleolus cured the patient.

Adult↗
PubMed1983

Possible teratogenicity of sulphasalazine.

Three infants, born of two mothers with inflammatory bowel disease who received treatment with sulphasalazine throughout pregnancy, were found to have major congenital anomalies. In the singleton pregnancy, the mother had ulcerative colitis, and the infant, a male, had coarctation of the aorta and a ventricular septal defect. In the twin pregnancy, the mother had Crohn's disease. The first twin, a female, had a left Potter-type IIa polycystic kidney and a rudimentary left uterine cornu. The second twin, a male, had some features of Potter's facies, hypoplastic lungs, absent kidneys and ureters, and talipes equinovarus. Despite reports to the contrary, it is suggested that sulphasalazine may be teratogenic.

Abnormalities, Drug-Induced↗
PubMed1983

Smoking and alcohol consumption during pregnancy: an epidemiological study in Tasmania.

Smoking and alcohol ingestion were analysed in 5100 women confined in Tasmania in 1981. This represented 70% of the total number of confinements. The incidence of smoking throughout pregnancy was 33.6%, and 2.7% of the women studied smoked at some time during pregnancy. Alcohol consumption in pregnancy was recorded for 55.9% of patients. However, 99% were only occasional drinkers. There was a statistically higher incidence in smoking habits in the age group 20 years and under, the unmarried and the lower socio-economic classes, whereas the reverse was true for alcohol consumption. The analysis provides a basis for the groups toward which programmes should be directed.

Adult↗
PubMed1983

Clinical and histologic findings in opportunistic ocular infections. Part of a new syndrome of acquired immunodeficiency.

White retinal opacities and ocular inflammation may be two of the early signs of a new syndrome of acquired immunodeficiency. This syndrome primarily affects young homosexual men and is characterized by acquired cellular immunodeficiency in infections with multiple opportunistic microorganisms in addition to Kaposi's sarcoma. The apparently innocent ocular findings may be the first harbingers of this devastating syndrome.

Acquired Immunodeficiency Syndrome↗
PubMed1983

Clinical and subclinical oculomotor findings in the Eaton-Lambert syndrome.

Five patients with the Eaton-Lambert syndrome were examined neuro-ophthalmologically. Three were studied using electro-oculographic saccadic velocity recordings. Four complained of blurred vision and all complained of ptosis during the course of their disease. Clinical examination revealed mild ptosis in three of the five patients. Saccadic velocities before exercise were normal. After saccadic exercise, an increase in velocity of up to 40% was noted in two of the three patients studied.

Aged↗
PubMed1982

Ophthalmoscopy of the retinal nerve fiber layer. Use in detection of neurologic disease.

Ophthalmoscopic examination of the retinal nerve fiber layer may demonstrate changes associated with a variety of diseases. These alterations are of four general types: slit or rake defects, sector atrophy, diffuse atrophy, and density changes in the nerve fibers themselves. With practice and the use of a bright source of "red-free" light, recognition of these alterations provides a bedside tool for evaluation of te anterior visual pathways.

Adolescent↗
PubMed1981

Abnormal visual-evoked potentials from eyes with optic nerve head drusen.

We evaluated 38 eyes (29 patients) with unilateral or bilateral optic nerve head drusen by means of visual field testing (static, tangent screen, and Goldmann perimetry), nerve fiber layer characterization (using red-free fundus photography), and flash visual-evoked potential testing. We found that 27 of 36 (75%) of the eyes with drusen had abnormal visual fields, 36 of 38 (94.7%) had abnormal nerve fiber layers, and 35 of 36 (97.2%) had abnormal visual-evoked potentials. The degree of abnormality on any one test did not reliably predict the results of either of the other two tests; however, there appeared to be an association between the visual-evoked potential aberrations and the retinal nerve layer deficits.

Adolescent↗