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Biomedical subjects

N M Merkle

Publications and source records attributed to N M Merkle.

22 records · Page 2Linked to original sources

[The role of enteral and parenteral feeding in cancer therapy].

The role of nutrition support as an adjunct to cancer treatment is discussed. Many patients with advanced cancer have demonstrable nutritional deficits, the reason is still unclear. Anorexia, taste abnormalities, pain and obstruction of the gastrointestinal tract can lead to malnutrition. Different modes of therapy, like surgery, radiotherapy and chemotherapy, sometimes deteriorate nutritional status. Several investigators have indicated, that nutritional support provides some benefit. There is no indication at the present time of any disadvantage of this method of treatment in relation to tumor growth. The potential indications and methods of nutritional support are pointed out.

Enteral Nutrition↗

[Postoperative and enteral feeding following abdominal surgery. Clinical study using a peptide diet].

To assess the value of early postoperative feeding with a chemically defined oligopeptide diet, 20 patients were examined after cholecystectomy. The patients were randomly selected for conventional treatment (water, electrolytes, and carbohydrates by intravenous route) or for feeding with the elementary diet (water, electrolytes, carbohydrates, fat short-chain peptides via a jejunal tube). The clinical and metabolic course of the ten patients fed with the elementary diet was good; they had a positive nitrogen balance by the second postoperative day. The results suggest that enteral tube feeding with a chemically defined oligopeptide diet is possible even in the early postoperative period after gastrointestinal operations and perhaps a definite alternative to parenteral nutrition.

Adult↗

Minitracheotomy: a new interventional technique for treatment of sputum retention.

Sputum retention causing pulmonary atelectasis, secondary pneumonia, and respiratory failure is a frequent complication particularly in patients recovering from abdominal and thoracic surgery. Physiotherapy and conventional therapeutic means like blind tracheobronchial and bronchoscopic suction applied to prevent and treat postoperative respiratory complications have been shown to not be completely effective. Minitracheotomy is a new alternative method for the treatment of sputum retention. Endobronchial suction can be performed as often as required, using a thin uncuffed tube (ID 4.5 mm) which is inserted into the trachea through the cricothyroid membrane under local anaesthesia. Since respiration occurs normally through the nose, mouth, and larynx these patients retain speech and the ability to cough. Complications are rare. Endobronchial suction via minitracheotomy is minimally invasive, more comfortable, and at least as effective as conventional bronchoscopic suction. It therefore has become a routine method used in the treatment of postoperative sputum retention in high-risk patients in many intensive-care units.

Humans↗