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Biomedical subjects

N M Blake

Publications and source records attributed to N M Blake.

67 records · Page 4Linked to original sources

Lactate dehydrogenase electrophoretic variant in a New Guinea Highland population.

Six examples of a variation in the LDH-A subunit have been detected in 408 samples from three exogamous clans in the New Guinea Highlands. The New Guinea variant is similar to the Memphis-4 variant. Origin of the New Guinea variant could not be traced by genealogy but it seems likely to have persisted for several generations.

Black People↗

Red cell enzyme and serum protein types in a population from Ndeni (Santa Cruz Islands).

Data for 14 red cell enzyme systems, haemoglobin and four serum proteins are presented for 351 people from the island of Ndeni in the Santa Cruz group of the British Solomon Islands Protectorate. The results support the view based on linguistic studies that the Ndeni population is derived from a mixing of older Papuan and later Austronesian-speaking peoples.

Blood Proteins↗

Red cell enzyme and serum protein types in the Watut Anga of Papua New Guinea.

Historically, the Angan populations of Papua New Guinea have maintained a strong isolation and absorbed limited genes from their neighbours. This lack of intermixing is reflected in their relatively homogeneous cultural, linguistic and genetic profiles. We have determined the electrophoretic variation at 26 red cell enzyme, serum protein and haemoglobin loci in the Watut Anga, a splinter group occupying the Upper Watut Valley of Morobe Province. Their genetic profile reveals the lack of a number-of variants, such as PGM2*10 and MDH*3, known to exhibit high frequencies in other highland populations. The average heterozygosity in the Watut is also much lower when compared with other Papua New Guinean populations. Their present numerical strength notwithstanding, it appears that the Angan populations have experienced population bottlenecks in their evolutionary history which may have accentuated their genetic divergence from other Papua New Guinean populations.

Adult↗