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Biomedical subjects

N M Bennett

Publications and source records attributed to N M Bennett.

At least 37 records · Page 2Linked to original sources

Hospital outbreak of multiresistant Staphylococcus aureus in Victoria, 1979-1984.

The outbreak of nosocomial infection caused by multiresistant Staphylococcus aureus (MRSA) strains in Victoria has been monitored by a continuing programme of collecting monthly statistics from all hospitals on new patients who have been either colonized or infected by these strains. Data collected during the period from November 1980 to September 1984 have been plotted on graphs. Whereas the prevalence of MRSA strains has remained virtually unchanged, the number of infections attributed to them appears to have gradually decreased since November 1982.

Australia↗

Epidemic polyarthritis acquired in Fiji.

Four cases of epidemic polyarthritis which was acquired in Fiji between April and July of 1979 are described. The manifestations of the illness were similar to those of the disease in Australia. Knowledge of the geographic distribution of this disease can be valuable in diagnosis, but it is likely that its range is not yet fully known.

Adult↗

Viral hepatitis and intrahepatic cholestasis of pregnancy.

Specific serological tests which are now available for the diagnosis of infection with hepatitis A and hepatitis B viruses, were used to distinguish viral hepatitis from other causes of liver disease in pregnancy. Forty-nine (51.6%) of 95 pregnant patients had viral hepatitis, 24 hepatitis A and 25 hepatitis B. The majority of patients (26 of 28) presenting before 22 weeks gestation had viral hepatitis. By contrast, 23 (34.3%) of the remaining 67 patients presenting with abnormal liver function tests at greater than or equal to 22 weeks gestation, had viral hepatitis; the majority of the remainder had features compatible with intrahepatic cholestasis of pregnancy. Although there were significant clinical and biochemical differences between the two groups, accurate diagnosis was only possible by using specific virological tests.

Adult↗

Does viral hepatitis cause aplastic anaemia?

The sera of six of seven patients with aplastic anaemia following "hepatitis" admitted to Fairfield Hospital, Melbourne, since 1954 were examined for serological evidence of infection by HAV or HBV, with negative results. We conclude that at present there is insufficient evidence to presume that infection with any of the hepatitis viruses predisposes to aplastic anaemia.

Adult↗

Diagnosis of leprosy in Victoria--a non-endemic area of Australia.

There have been at least 70 cases of leprosy in Victoria since 1950; the occurrence of 40 of these in the last seven years indicates that the disease is no longer rare in this State. The diagnosis was delayed in most patients, the average period of time between development of symptoms and diagnosis being 28 months. The most common presentations among these patients emphasize the point that a diagnosis of leprosy should be considered in patients who are suffering either from chronic skin diseases which are atypical and have not responded to therapy, of from localized disturbances of skin sensation.

Adolescent↗

Studies with a live influenza A vaccine in army personnel.

A live attenuated influenza A vaccine, produced from an inhibitor-resistant recombinant strain, was administered intranasally to 46 volunteers from the Army during the southern winter of 1973. To compare the acceptibility, immunogenicity and efficacy of this vaccine, a killed subunit vaccine was administered to 20 volunteers, and an intranasal placebo to 45 others. Results indicate that the live intranasal vaccine was as well tolerated as the killed vaccine and that there was no evidence of shedding of virus from the nose in the 14 days following vaccination. Both the killed and the live vaccines stimulated the production of circulating haemagglutination-inhibition antibody, but antibody to neuraminidase was induced only by the live vaccine. No conclusions could be drawn about the efficacy of the two vaccines in producing local antibodies because these were largely undetectable by the methods used. Volunteers were followed for a 12-month period, which included the 1973 and 1974 influenza seasons, and an attempt was made to determine the virological aetiology of all their respiratory infections during this period. Epidemic influenza did not occur in thepopulation group from which these volunteers were drawn, so the comparative protection rates of the two vaccines could not be assessed.

Antibodies↗

Murray Valley encephalitis, 1974: clinical features.

Of the 58 patients who developed Murray Valley encephalitis (MVE) during 1974, 22 were admitted to Fairfield Hospital, Melbourne. The patients were of all ages, but the disease was most common in children. Calculations suggest that the incubation period of MVE is from one to four weeks. The severity of brain damage varies considerably; 11 patients recovered almost completely, seven had severe residual damage and four patients died. There are no special features which distinguish MVE from any other form of encephalitis. The survival of five of eight patients who required artificial respiration suggests that patients with suspected MVE should be transported at an early stage to a hospital where artificial respiration is available if necessary. There is no evidence that infection with the MVE virus can cause clinical manifestations of a disease other than acute encephalitis.

Adolescent↗

On the aetiology of whooping cough.

The results of routine bacterial and viral studies on 483 patients with whooping cough, investigated at one hospital over a five year period are presented. The possible role of respiratory viruses in the aetiology of the disease is discussed.

Adenoviridae↗