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Biomedical subjects

N L Zil'bert

Publications and source records attributed to N L Zil'bert.

8 recordsLinked to original sources

[Study of regional differences in the population morbidity and mortality from the standpoint of geographical latitude syndrome].

Based on a large material of international and Soviet investigations as well as on the data of official statistics, the authors analyze the main characteristics of the population morbidity and mortality depending on the geographic latitude. It has been demonstrated that with the moving away from the equator, the intensive growth of the general mortality is observable both in the USSR and in the countries of Europe and America as is of the lethality due to malignant neoplasms, circulatory diseases together with an increase of the lethality because of suicides. At the same time there is a dramatic lowering of the infantile death rate and of the mortality from infectious and parasitic diseases. It has been revealed that the incidence of arterial hypertension, alcoholism and drug addiction associated with the geographic latitude. Different factors that may underlie the regularities established are under analysis. An idea is advanced of the geographic latitude syndrome which is of paramount methodological importance for preventive medicine.

Adolescent↗

[Method of detecting the early stages of heart failure in arterial hypertension patients in prophylactic studies in an unselected population].

A total of 569 subjects (91.2% response rate) were examined from a 5% random sample of 40 to 64 year-old men and women in the framework of a prophylactic program on hypertension control. There are 181 patients (31.8%) suffering from arterial hypertension (blood pressure 160/95 mm Hg and above). In 111 of them cardiac insufficiency was diagnosed by standard clinical methods and in 60 patients by bicycle spiroergometry. Two-stage bicycle spiroergometry has some advantages over one-stage test: work load volume, physical adaptation coefficient, time of heart rate recovery were increased by 202.7%, 124.4% and 220%, respectively, the exercise tolerance being improved. Cardiac insufficiency was found in 35.3% of cases, latent IA stage, diagnosed by bicycle spiroergometry, being revealed in 18.3%, IB stage in 10.0%, IIA stage in 3.4% and IIB in 3.6% of cases.

Adult↗

[Pyridoxylate treatment of athletes with chronic myocardial overexertion].

Twenty-five highly skilled athletes with chronic stage I or II myocardial overexertion were examined. It was established that pyridoxilate produced a good therapeutic effect despite the fact that the athletes went on with their sport activities. On the background of the treatment the ECG and the indices of cardio- and hemodynamics and gas exchange improved and the physical efficiency grew. No essential difference was found in the effectiveness of pyridoxilate when it was administered by different routes. Side-effects of treatment were not observed.

Blood Pressure↗

[Use of pyridoxylate for treating chronic coronary insufficiency].

A total of 49 patients with chronic ischaemic heart disease (38 of whom had previously survived myoca dial infarction) were treated with Piridoxylate administered intramuscularly and orally. The treatment resulted in an improvement of the state of 2/3 of the patients, positive ECG shifts, improvements of cardio- and haemodynamics at rest and under physical exercises. In half of the patients an increased tolerance of physical exercises was noted. No side-effects of Piridoxylate therapy were observed.

Administration, Oral↗

[Effect of propranolol on hemodynamic shifts and respiration during physical exertion in patients with hypertensive disease].

An examination of 25 patients with hypertensive disease of the I-II stage proved that following propranolol treatment the systolic and mean arterial pressure, the rate of cardiac contractions and the minute blood volume accrue on physical effort to a lesser extent, and the circulation time, diastolic pressure and peripheral resistance ot the blood flow-to the same degree as before the medication. Changes in the phasic structure of the left ventricle of the heart in physical exertion are less marked than they were prior to the treatment. Propranolol does not materially change the level of the oxygen consumption on effort; the lactic acid level and the ratio lactate/pyruvate in the blood rise against the background of the medication with this drug to a some-what lesser degree than before the treatment.

Blood Pressure↗