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Biomedical subjects

N L Kushch

Publications and source records attributed to N L Kushch.

At least 163 records · Page 9Linked to original sources
PubMedDate not supplied

[Immune shifts and their correction in the extremely severe course of diffuse suppurative peritonitis in children].

Clinical and immunological studies of 65 patients with extremely severe disseminated suppurative peritonitis have revealed profound disturbances in their immune status. A considerable (2.5-3-fold) decrease in phagocytosis and complement activity, a drastic drop in T-, B-lymphocyte and T-helper content and a depression in T-lymphocyte functional activity have been observed. All this was accompanied by the activation of allergic and autoimmune reactions. Single transfusion of extracorporally X-ray-irradiated autoblood (5-7% of circulating blood volume) promoted an earlier normalization of the patients' critical condition and a prompt correction of the immune shifts.

Adolescent↗
PubMedDate not supplied

[Sex determination in intersexuality in children].

The authors performed the treatment of 124 patients with various patterns of androgyny: 51 with false female and 64 with false male hermaphroditism, and 9 patients with true hermaphroditism. Karyotyping of 31 studied patients revealed karyotype 46XY in 13 persons, mosaic type 45X0/46XY in 2 persons with false male hermaphroditism. In patients with false female hermaphroditism karyotype 46XX was identified in 12 persons. In patients with true hermaphroditism karyotype 46XX was identified in 2 subjects and 47XYY in 1 examinee. The authors supposed the term "gonadal" sex to be a determinant for the identification of the sex status in persons with various patterns of androgyny as it could define a "gamete" and "hormonal" sex. The key problem of androgyny is the detection of true causes of various sexual abnormalities and the technique of their prevention. A true "gonadal" sex should be identified during the first month of a child's life. It would permit one to start timely cortisone treatment for adrenopathic false female hermaphroditism an adequate registration of a child: proper name (documented sex), timely examination of its internal genitalia (removal of those sexual organs that contradict to the sex chosen) and planning the further scope and terms of necessary plastic surgery as well as alleviating severe emotional and psychic traumas of a child's parents.

Adolescent↗