Biomedical subjects
Publications and source records attributed to N L Kushch.
The results of neurohistologic investigation of lymphangiomas, removed in 68 children, are presented. At the early age in children, the changes in neural fibers of lymphangiomas correspond to reaction of irritation. With increasing of the age, the pronouncement of the destructive processes in the neural fibers increases, leading to hypo- and anervia of the tissues of lymphangiomas.
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Long-term results and indices of immune reactivity in 30 patients who had splenectomy performed in childhood for trauma of the spleen were studied. The organ-preserving approach for this pathology is substantiated. Autotransplantation of the spleen pulp into the pocket formed from the greater omentum was performed in 5 children during splenectomy for trauma of the organ. An original device was used for better preparing the autotransplant. The postoperative period was without complications. The laboratory, sonographic and scintigraphic examinations have shown high functional activity of the transplanted spleen tissue.
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Our clinical material has shown that results of organ-preserving operations on patients with doubling of the kidneys and vesicoureteral reflux are dependent on a number of factors. The leading factors are: degree of pathomorphofunctional alterations of the calyceal-pelvic system and parenchyma of the kidneys, the presence of pyelonephritis. After operations all the patients should be followed-up at dispenseries.
The authors have shown that direct transfusion of blood is of considerable significance for the improvement of results of treatment. The patient's state quickly improved, the course of treatment was more favourable, the appearance of chronic forms was considerably less and the percentage of invalidization of children became lower.
An examination of 46 patients has shown that the enzymatic status of circulating leukocytes of blood is a highly informative criterium which allows to judge about the pyo-inflammatory process, its spread, degree, reactivity of the patient's organism, efficiency of the therapy performed, prognosis of the disease.
Under study were results of the surgical treatment of 306 patients with various defects of the colon (Hirschsprung's disease, dolichosigmoid, dolichocolon, primary megarectum). In 158 of the patients the Duhamel operation was used, 148 patients were operated on after Soave. Early postoperative complications were established in 13 patients (4.2%), late complications were found in 15 patients (4.9%). The character of the early and late complications was dependent on the kind and technique of the operation.
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A method of surgical treatment of 47 patients with microphallus is described. There are two kinds of the surgical treatment of microphallus depending on its form. A new operative method is proposed for a dystopic form. Good long-term results were obtained.
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Under study were indices of the immune reactivity and infectious morbidity in 30 persons subjected to splenectomy in childhood for traumatic rupture of the spleen. They were shown to have lower resistance to infections. Children after splenectomy need a continuous dispensary observation. Prophylactic measures require further development. The most perspective method of preserving the functioning splenic tissue in the organism after trauma of the organ is thought to be autotransplantation of the splenic pulp.