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Biomedical subjects

N L Jacobson

Publications and source records attributed to N L Jacobson.

43 records · Page 3Linked to original sources
PubMed1966

Influence of diet and age on bacterial counts of ileal digesta and feces obtained from young calves.

The numbers of total aerobes, total anaerobes, and facultatively aerobic lactobacilli, streptococci, and coliform bacteria were determined in samples of ileal digesta and feces from calves 0, 3, 6, 9, and 12 hr after feeding milk, or milk with sucrose or starch added. Differences in the flora could be attributed to diurnal variation (time from feeding to sampling), source of the sample (ileal versus fecal), nature of the dietary carbohydrate (lactose versus lactose plus sucrose versus lactose plus starch) and age of the animal (on a diet of milk plus sucrose).

Animals↗
PubMedDate not supplied

Vitamin A inhibits some aspects of systemic disease due to local x-radiation.

We have previously reported that supplemental vitamin A ameliorates the stress response to a wide variety of noxious agents. The present study was carried out to determine how supplemental vitamin A influences the course of radiation sickness in C3H female mice subjected to 3000 R irradiation of one lower hind limb. All mice ingested a chow diet containing about 13,000 units of vitamin A/kg diet (about half as preformed vitamin A and half as beta-carotene) which supports normal growth, development, and reproduction of normal mice. One hundred fifty thousand units of vitamin A/kg chow was added for the vitamin A supplemented mice. All mice ate and drank ad libitum. The supplemental vitamin A feeding was begun either 3 days before radiation or immediately after radiation. There were no significant differences in the effects of these two regimens. The supplemental vitamin A prevented the weight loss, moderated the adrenal hypertrophy, prevented the thymic involution, and lessened the lymphopenia due to radiation. We conclude that supplemental vitamin A has both prophylactic and therapeutic benefits in radiation-induced disease.

Adrenal Glands↗