Progression of radiological changes was noted in 19 (22.1%) of 86 cases of relapsing or chronic pancreatitis followed by serial pancreatograms. The initial feature of chronic pancreatitis was focal minimal pancreatitis, characterized by an irregular dilatation of several side branches on the pancreatogram. Some patients with focal minimal pancreatitis demonstrated progression of the extent and severity of changes only in side branches while others progressed further to moderate or advanced chronic pancreatitis showing changes in the main pancreatic duct. Most of the progressive cases were alcoholic, and some showed progression to advanced pancreatitis within 4 years. Rapid progression of radiological changes was associated with relapses of acute pancreatitis. No remarkable changes were observed in many non-alcoholic patients, whereas some cases complicated with gallstones showed progression of disease in the side branches during a follow-up period of 3-7 years.

Aged↗

PubMedDate not supplied

Diagnostic value of endoscopic retrograde pancreatocholangiography for carcinoma of the pancreas [proceedings].

Explore the source record for details and available documents.

Cholangiography↗

PubMedDate not supplied

Endoscopic cytology of the esophagus, stomach and pancreas.

Cytology and biopsy under direct vision using a fiberscope as microscopic diagnostic procedures for carcinoma of the esophagus and stomach were described, and results of cytology were evaluated as compared with the results of biopsy. The diagnostic accuracy of brushing cytology under direct vision using a fiberscope was 97% in 116 cases of esophageal carcinoma and 78% both in 119 patients with carcinoma of the gastric cardia and in 63 patients with gastric carcinoma exclusive of the cardia. The diagnostic accuracy for cytology of pancreatic juice collected by cannulation in 36 patients with carcinoma of the pancreas was 56%: 79% for carcinoma of the head of the pancreas, but only 35% for carcinoma of the body and/or tail. For the esophagus and stomach, the diagnostic accuracy of direct vision biopsy has become almost as high as with cytology. As such biopsies are easily performed, esophagogastric cytology has become in our clinics a supplementary routine to the biopsy, and is done in a limited number of cases in which the biopsy failed or was not appropriate. However, cytology of the pancreas, in which biopsy is difficult, is important as the only microscopic diagnostic procedure. There, the development of newer instruments and the improvement of techniques of cell collecting are required, as is the development of expertise in the interpretation of cells from pancreatic carcinoma, in which the diagnostic accuracy is still relatively low.

Biopsy↗

PubMedDate not supplied

The diagnosis of pancreatic cancer by pancreatic juice cytology.

Cytologic examination of pancreatic juice collected during cannulation was performed on 105 patients. Positive results were obtained in 23 of 44 cases (52.3%) of carcinoma of the pancreas. Cytologic specimens were collected by direct suction, washing with saline, aspiration after secretin stimulation and brushing. Washing with saline (63.2%) and aspiration after secretin stimulation (51.3%) gave higher positive results than did the other two methods. Positive results when obtained in carcinoma of the head in 12 of 17 cases (70.6%) and in carcinoma of the body and tail in 9 of 24 cases (37.5%). The results were better in carcinoma of the head, and it is necessary to further improve the method of collection in carcinoma of the body and tail.

Cholangiopancreatography, Endoscopic Retrograde↗