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Biomedical subjects

N Kreitman

Publications and source records attributed to N Kreitman.

At least 19 recordsLinked to original sources
PubMed1993

Risk factors for suicide and undetermined death among in-patient alcoholics in Scotland.

Approximately 32,000 patients, representing all those discharged alive from inpatient psychiatric care for alcoholism in Scottish hospitals between 1974 and 1983, were traced for up to 10 years by means of a national record-linkage study in order to ascertain the frequency of suicide and undetermined deaths. The cumulative mortality from these causes was 1.17% at 5 years and 2.01% at 10 years. Several risk factors were investigated, using survival analysis techniques. Sex, age, social class (males only) and marital status were not found to be useful predictors, but the different secondary diagnoses recorded at discharge were associated with major variations in outcome. Attention is drawn to the prognostic importance of a secondary diagnosis of both affective disorders and personality disorders, and some implications of the findings are noted concerning attempts to construct population models linking alcoholism, demographic characteristics and suicide.

Adolescent↗
PubMed1991

Association of age and social class with suicide among men in Great Britain.

STUDY OBJECTIVE: The aim was to investigate suicide and "undetermined" deaths by age, economic activity status, and social class in Great Britain among males of working age. DESIGN: The study was a cross sectional analysis of Registrar General's data for England and Wales around 1981, repeated for around 1971, and for Scotland around 1971 and 1981. MEASUREMENTS AND MAIN RESULTS: For England and Wales around 1971, suicide and undetermined death rates showed a progressive increase with age and a markedly higher rate in the lower social classes. A significant interaction effect was identified in the central age groups of the lower occupational categories. This interaction was confirmed in the remaining three data sets, notwithstanding some differences in the profile of age specific mortality. Other findings included a higher standardised mortality ratio for the economically inactive, who also showed an earlier peak in age specific mortality, and a relative concentration of undetermined as compared to suicide deaths in the lower social classes, but not all these further results were fully replicated. CONCLUSIONS: There is a concentration of suicide and undetermined deaths in the middle age groups of the lower social classes. Plausible explanations include both the social drift and the social genesis hypotheses, the latter including the effects of long term unemployment.

Adolescent↗
PubMed1991

The construction and selection of predictive scales, with special reference to parasuicide.

Issues concerning the use of predictive and screening instruments include the difficulties posed by temporal changes in the base rates for the behaviour of interest, the possible advantages of using three rather than the customary two risk categories, and the desirability of specifying in advance the proportional sizes of the risk subgroups. A method is proposed for constructing and assessing tripartite risk scales, and a new scale for predicting the repetition of parasuicide, with the results of a prospective validation study, is reported.

Adult↗
PubMed1990

Long term trends in parasuicide and unemployment in Edinburgh, 1968-87.

Aggregate- and individual-level trends in parasuicide and unemployment among men and women resident in Edinburgh during the years 1968-87 are reported. During the first half of the period unemployment and parasuicide rates increased in parallel (r = 0.91, P less than 0.001 among men; r = 0.82, P less than 0.01 among women). However, while unemployment continued to rise after 1977, parasuicide rates tended to fall (r = -0.83, P less than 0.001 among men; r = -0.38, NS among women). It could be shown that the reversed relationship between parasuicide and unemployment after 1976 was not due to changes over time in the validity of the local unemployment rate as a marker of economic conditions. Suggested explanations for the falling parasuicide rate in Edinburgh include the possibility of a "threshold" effect and the influence of other (non-economic) factors. The rate of parasuicide among the unemployed fell, especially after 1973, while the rate among the employed rose until 1976-7, thereafter tending to fall. The relative risk (rate among the unemployed/rate among the employed) declined until 1979, since when it has fluctuated at about 10. The highest rate of parasuicide was consistently found among the long-term unemployed.

Adolescent↗
PubMed1989

Alcoholic and non-alcoholic liver disease in relation to alcohol consumption in Scotland, 1978-84. Part I: Epidemiology of liver diseases.

A common strategy in epidemiological studies linking alcohol consumption in the general population with liver cirrhosis mortality is to use non-specific cirrhosis mortality rates in which alcoholic and non-alcoholic causes of death are not distinguished. Evidence is presented from Scottish mortality data for 1979 to 1984 that the two forms of cirrhosis have quite different epidemiological profiles. Similar findings emerge from morbidity data. The two forms of disease should be distinguished in future studies in which liver cirrhosis is used as a proxy for consumption, despite the manifest shortcomings of currently available data.

Adult↗
PubMed1988

Suicide, age and marital status.

A new data set concerning suicide in relation to marital status for Scotland, 1973-83, is presented. The effects of age-standardization on marital status rates and of marital status standardization on age-specific rates are both elucidated. The difficulties of drawing conclusions from marital status rates for suicide are outlined. Nevertheless, the data suggest that the importance of the widowed state has been underestimated and that it appears that the relative risk for suicide associated with divorce has probably been decreasing among Scottish men over the study period.

Adolescent↗
PubMed1988

Recent clinical and epidemiological trends in parasuicide in Edinburgh and Oxford: a tale of two cities.

This is a report of clinical and epidemiological trends in parasuicide in Edinburgh and Oxford over the period of 1976 to 1984. Rates of parasuicide declined in both cities, but more markedly among women than men. Male rates tended to be higher in Edinburgh and female rates higher in Oxford. Age-specific rates were similar for the two cities in 1983-84, with peak rates for females among 15-19 year olds and those for males among 20-24 year olds in Edinburgh and 25-34 year olds in Oxford. Parasuicide incidence was higher in lower social class groups and among the unemployed in both cities. During the study period there was a massive decline in barbiturate overdoses, a more modest decline in minor tranquillizer overdoses but, in Oxford, a marked increase in self-poisoning with paracetamol. By the end of the study period the proportion of patients receiving a diagnosis of drug addiction had doubled in Edinburgh, although it had remained fairly constant in Oxford. There were differences in patterns of aftercare offered to patients in the two cities; these almost certainly reflect differing clinical policies.

Adolescent↗
PubMed1988

Repetition of parasuicide: an epidemiological and clinical study.

The dramatic clinical presentation of parasuicide tends to deflect attention from the repetitive pattern of this behaviour in many patients. In an epidemiological study of annual cohorts of parasuicides for 1972, 1977, and 1982 admitted to the Regional Poisoning Treatment Centre, Edinburgh, it was found that for certain subgroups of the population 'repeaters' were actually commoner than 'first-ever' patients, and a number of risk factors were identified, of which social class was particularly important. The clinical characteristics of patients distinguished by their frequency of repetition were also described, with special attention to the stability of these differentiating features over time. It is suggested that the habitual repeater requires closer study, and that the factors which lead to initiation into a parasuicidal 'career' are not necessarily those which conduce to repetition.

Adolescent↗
PubMed1985

Neurosis divisible?

Explore the source record for details and available documents.

Anxiety Disorders↗
PubMed1985

Parasuicide and unemployment among men in Edinburgh 1968-82.

The ecological association between unemployment and parasuicide rates among males in Edinburgh over the period 1968-82 was positive and highly significant (r = 0.77). Similarly, the two rates were found to be correlated across the city wards in 1971 (r = 0.76) and even more strongly in 1981 (r = 0.95). Throughout the period the parasuicide rate among the unemployed was nearly always more than 10 times higher than that among the employed. The long-term unemployed were at much higher risk than those out of work for lesser periods, although the impact of recent job loss was marked. Population attributable risk has shown a tendency to rise in line with the upward trend in the unemployment rate, despite the decline in relative risk over the period. The findings were considered consistent with the view that unemployment increases the parasuicide rate.

Cross-Sectional Studies↗