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Biomedical subjects

N Kaufman

Publications and source records attributed to N Kaufman.

At least 73 records · Page 4Linked to original sources
PubMed1978

Striatal nondopaminergic neurons: possible involvement in feeding and drinking behavior.

Intracaudate injections of kainic acid destroy striatal neurons containing acetylcholine and gamma-aminobutyric acid but leave dopaminergic nerve terminals in this brain region intact. Rats injected with the drug are aphagic and adipsic, and have other behavioral abnormalities strikingly similar to those seen in animals with lesions in the dopaminergic nigrostriatal bundle.

Animals↗
PubMed1977

Two microsomal-associated iron-binding proteins observed in rat small intestinal cells during iron absorption.

Acrylamide gel electrophoresis of microsomal protein obtained from rat small intestinal mucosal cells, after an injection of [3H]leucine, demonstrated increased quantities of two soluble iron-binding proteins during iron absorption, one with a high molecular weight (about 400 000) and the other of intermediate molecular weight (80 000). Both proteins were present in a ribosomal-enriched sub-fraction obtained during purification of the microsomal membrane but were not identified among the purified membrane proteins.

Animals↗
PubMed1976

Effect of iron absorption on plasma membrane proteins of small intestinal mucosal cells from iron-deficient rats.

Plasma membrane protein was isolated from small intestinal mucosal cells of normal and iron-deficient rats during iron absorption and examined by acrylamide gel electrophoresis. Two proteins were present in increased amounts in the iron-deficient animals 10 min after administration of iron; uptake studies with 3H-leucine indicated that each had been newly-synthesized. The molecular weights of the proteins were about 60,000 and 300,000.

Animal Feed↗