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Biomedical subjects

N Kameda

Publications and source records attributed to N Kameda.

47 records · Page 3Linked to original sources
PubMed1988

Primary osteosarcoma of toe phalanx: first documented case. Review of osteosarcoma of short tubular bones.

A case of a sclerosing variant of osteosarcoma of a toe phalanx is reported in a 28-year-old man. This represents the first reported case of osteosarcoma of any kind at this site. This is based on a review of 4,214 cases of conventional osteosarcoma. The reason for the extraordinary rarity in toe or hand phalanges is unknown although osteosarcoma is the second most common primary tumor of bone. Since the neoplasm had minimal signs of cytologic anaplasia, it was originally mistaken for and treated as an osteoid osteoma. The lesion recurred and extended into soft tissues. Reevaluation revealed the tumor to be an osteosarcoma, sclerosing variant with "normalization" of nuclei. The lesions that this tumor should be distinguished from are osteoid osteoma and osteoblastoma.

Adult↗
PubMed1987

Parasellar chondroma: a case report.

A case of a 19-year-old man with a right parasellar chondroma examined with computed tomography (CT) and nuclear magnetic resonance (NMR) scan is reported. The literature about CT and NMR scan findings of intracranial chondroma is reviewed. Typical CT findings are a round, high density mass with calcification, that is only slightly enhanced by contrast medium.

Adult↗
PubMed1987

Primary leiomyosarcoma of bone. A case report and review of the literature.

A 62-year-old female with primary leiomyosarcoma of the left femur is reported with a review of 21 cases reported in the literature. The resected specimen showed that the tumor extended from the femoral head to the diaphysis for 13 cm in length. The tumor showed mainly intramedullary proliferation, but extraosseous growth was also noted at the great trochanter. Microscopic examination revealed well differentiated leiomyosarcoma characterized by interlacing bundles of fusiform cells with eosinophilic cytoplasm and rod-shaped hyperchromatic nuclei. PAP stain of actin on the tumor cells was positive. On electron microscopy, microfilament of 6-8 nm in diameter, dense bodies, pinocytotic vesicles, marginal attachment plate, and basal lamina were noted. The patient died with pulmonary metastasis, 1 year and 7 months after the operation. An autopsy showed metastases in the right pelvic cavity and bilateral lungs, and confirmed the primary site to be the left femur.

Female↗
PubMed1985

[Hematoma of the pineal region: a case report].

A 44-year-old man came to our clinic, complaining of slowly progressive disturbance of visual acuity and of ocular movement. This patient suffered from headache, narrowing of visual field and polyuria about 20 years ago, and received surgical and radiation therapy under the diagnosis of pituitary adenoma. Clinical symptoms and signs of this patient, except for bitemporal hemianopsia, almost completely disappeared after these treatment. The detailed information about the histology and radiation dose are not available at the present time. CT scan in our clinic revealed a round low-density area at the suprasellar region and a high density area at the left quadrigeminal cistern. Pineal calcification was compressed to the right about 2-3 mm from midline. This high density mass were not enhanced with contrast medium. Vertebral angiography showed a slight lateral displacement of the left medial posterior choroidal artery. Specimen of tissue removed 20 years ago was reexamined but definitive diagnosis could not be established. Presumptive diagnosis of an ectopic pinealoma in the suprasellar region treated successfully 20 years ago, and its recurrence in the pineal region was made. On May 24, the patient underwent a posterior fossa craniectomy and the pineal region was explored via the infratentorial supracerebellar approach. On sectioning the precentral cerebellar vein, yellowish mass was seen in the quadrigeminal cistern. Aspiration of this mass yielded dark red liquid hematoma. Incising into the capsule, a dark brownish mass of about 4g was removed en bloc.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1985

Myxoid angioblastomatosis of bones. A case report of a rare, multifocal entity with light, ultramicroscopic, and immunopathologic correlation.

An example of multicentric, skeletal, myxoid angioblastomas in a Japanese woman is reported. The disease was symptomatic at age 12 years and was characterized by slowly progressive, multiple, lytic bone defects. In addition the patient had juvenile hypertension, and, at age 20 years, had focal brain infarction. The primitive vascular nature of the process was supported by the following observations: occasional erythrocytes within cytoplasmic lumina and capillary-like cellular tubes; Weibel-Palade bodies, numerous pinocytotic vesicles, prominent microvilli, elaborate intercellular contacts, desmosomes, and numerous arrays of fine intracytoplasmic filaments by electron microscopy; and, in addition, Factor VIII positivity. The clinical findings in this case are more consistent with a multicentric, rather than a metastatic process. The name myxoid angioblastomatosis of bones is appropriate.

Adult↗
PubMed1984

[A quantitative morphologic study of cancellous bone--comparative study between physiological and pathological bone loss in autopsy cases].

The morphologic measurement of bone volume was made by using the lower lumbar vertebrae of 905 cases which were selected from 1,200 consecutive autopsy cases. The tendency and the degree of bone loss, under various pathological conditions and for aging, were compared and examined. Microscopic specimens of the lumbar vertebrae without bone marrow were used as source material and the dimensional ratios of the trabecular bone were calculated by video image processor (VIP). It is already well known that disappearance of transverse trabeculae first occurs in the progress of osteoporotic change, but in this study no clear difference appeared in the comparison of the dimensional ratios between the transverse and vertical trabeculae. On comparison between males and females in the control group, the loss of bone volume in females starts in the fifth decade with a rather rapid progress, while it starts gradually from the sixth decade in males. As regards the group with the diseases compared, the loss of bone volume appears very high for every age with high dose steroid hormone therapy and chronic renal failure but the group characterized by hypertensive vascular disorders showed an insignificant difference in comparison to the control group. In the group with malignant tumors, with liver cirrhosis and with heavy drinkers, the loss of bone volume appears to be considerable in younger individuals but no difference from the controls could be found in older individuals. In the group with diabetes mellitus, the bone volume appears to a high degree in younger individuals and the loss of bone volume makes for an accelerated increase in older individuals. This tendency is very different from the other diseased group. It can be considered that the mechanism of bone loss is accelerated with aging and various pathological factors together.

Adolescent↗
PubMed1984

[A case of highly atypical hyperplasia--difficult to differentiate from carcinoma].

We present a 51-year-old nulliparous woman with highly atypical hyperplasia of the uterus induced by the prolonged use of exogenous estrogen. The patient was given nearly 1,415 mg of estradiol dipropionate intramuscularly for over 23 years after operation for bilateral ovarian cysts. She complained of vaginal bleeding and diagnostic endometrial curettage revealed highly atypical hyperplasia which was difficult to differentiate from well differentiated adenocarcinoma. On hysterectomy, atypical tissues were limited to the upper part of the posterior wall of the uterus with no muscle invasion.

Adenocarcinoma↗
PubMed1979

Clinicopathological study of soft tissue tumors.

Clinical aspects of patients with soft tissue tumors encountered at the Department of Orthopaedic Surgery, Toho University over a 15 year period between 1961 and 1976 were analyzed. Accurate clinical records and histological findings were available in 91 patients, 80 of whom had benign tumors and 11 of whom had malignant ones. Recurrence was seen in 7 of the 80 patients with benign tumors. The prognosis was poor in those with malignant tumors as expected, especially in those with rhabdomyosarcoma.

Adolescent↗
PubMed1978

Diffuse infantile fibromatosis.

A boy 15 months old with diffuse infantile fibromatosis in the thigh is reported. A rapidly growing tumor in the right thigh was the only clinical manifestation, suggesting a malignant soft tissue tumor. Macroscopically, the lesion in the medial vastus muscle with an illdefined border gave a pepper and salt appearance. Histologically, the lesion was characterized by an abnormal proliferation of fibroblasts accompanied by some fibrosis, infiltration of chronic inflammatory cells, formation of lymphoid follicles, proliferation of capillaries and the presence of a small number of mature fat cells. No evidence of recurrence is found at present one and half years after operation.

Fibroma↗