Biomedical subjects
N K Soni
Publications and source records attributed to N K Soni.
Gustotoxicity of bleomycin.
50 patients with advanced malignancy treated with bleomycin were assessed for taste abnormality. 5 (10%) cases were found to have some degree of taste impairment. Gustation sense returned to normal within 10-12 weeks following discontinuation of bleomycin therapy. The possible pathophysiology of gustotoxicity is discussed in the light of the available literature.
Pregnancy tumor of the middle ear.
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Scleromatous lymphadenitis.
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A few points in the management of juvenile nasopharyngeal angiofibroma.
A few points based on our experience on 100 cases of nasopharyngeal angiofibroma are described, which are found very useful in the successful removal of nasopharyngeal fibroma. A new technique for the control of haemorrhage by a muscle graft immediately after the removal of an angiofibroma is advocated.
An unusual tumour mistaken as a lingual thyroid (a case report).
A rare case of benign mass with hypertrophic sero-mucinous gland presenting as a tumour at the junction of the anterior two-thirds and the posterior third of the middle of the tongue is reported, which is found to be of great academic interest because of its unique situation of that of a lingual thyroid and its characteristic histological picture. The salient features of the lesion are discussed.
Hansen's disease and olfaction.
The sense of smell was assessed in a group of 50 leprosy patients. It was found that 40% of the patients showed a mild to complete impairment of the smell sense (anosmia) which was related to the systemic clinical state and to the severity of nasal lesions. Possible reasons for anosmia in leprosy patients are discussed. It has been observed that anosmia may be the presenting feature of leprosy. Most leprosy patients are not aware of olfactory disturbances, and anosmia may be missed unless specifically looked for. It is emphasized that leprosy should be considered an important cause of anosmia, at least in endemic areas, and in an anosmic patient leprosy should be always excluded.
Assessment of anosmia.
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Bilateral transitional-type inverted papilloma of the nose and paranasal sinuses.
An uncommon bilateral transitional-type inverted papilloma of the nose and paranasal sinuses is presented, and the salient features of the lesion are discussed. The patient is well and without any signs of recurrence in either side of the nose more than two years after the first diagnosis and complete surgical excision of both tumours. Commonly unilateral, this tumour may occasionally be bilateral. In the present communication an uncommon case of bilateral inverted transitional-type papilloma, with a long history of allergy, is described with some comments on its pathogenesis.
Carcinoma of the tongue in a young child of eleven years.
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Unusual presentation of rhabdomyosarcoma of the nasopharynx.
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Disturbance of taste in leprosy.
The sense of taste was assessed in a group of 30 leprosy patients. The method used and the results are presented. Twelve patients (40 per cent) showed some degree of impairment of taste sensation and this was shown to be related to the severity of the disease. The possible reasons for the loss of taste are discussed.
Gustatory otorrhoea due to misdirection of regenerated nerve fibres.
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Carcinoma of the oesophagus in an eight-year-old child.
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Foreign body of the tonsil.
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A vegetative foreign body of the subglottic region.
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Massive metastatic retinoblastoma of the parotid gland.
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A massive sublingual--cervical dermoid.
An unusual case of a massive sublingual-cervical dermoid is presented. The salient features of the condition in relation to its incidence, embryology, pathology, symptomatology and management are discussed.