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Biomedical subjects

N J Williams

Publications and source records attributed to N J Williams.

35 records · Page 2Linked to original sources
PubMed1985

Studies on vitamin D binding protein in the nephrotic syndrome.

We studied the properties of vitamin D binding protein in plasma and urine from nine patients with nephrotic syndrome. Samples were incubated with 25-[3H]hydroxyvitamin D3, after which we determined binding capacity and apparent dissociation constants. Binding capacity was markedly less in plasma from patients with nephrotic syndrome than that from normal subjects, but binding affinity was unchanged. Specific binding of 25-hydroxy[3H]vitamin D3 could be demonstrated in urine from all the nephrotic patients, and sucrose density-gradient analysis of these urines revealed a single binding peak with sedimentation characteristics similar to those of vitamin D binding protein in plasma.

Adult↗
PubMedDate not supplied

The curved-bristle toothbrush: an aid for the handicapped population.

This study was undertaken to assess the comparative effectiveness of two toothbrushes in the removal of plaque in an institutionalized, handicapped population. The two methods were: a conventional toothbrush using the Modified Stillman Method; and a curved-bristle toothbrush using the scrubbing technique recommended by the manufacturer. Subjects selected were profoundly retarded individuals, incapable of self-brushing skills. According to random selection, subjects' teeth were brushed by trained personnel with either the curved bristle or the conventional toothbrush. Results demonstrated that the curved-bristle toothbrush was as effective as the conventional toothbrush when used by trained personnel.

Adolescent↗