Search PubMed⌕ Search

Biomedical subjects

N J Smith

Publications and source records attributed to N J Smith.

162 records · Page 9Linked to original sources
PubMedDate not supplied

Combined clinical and laboratory studies with carbenicillin and ticarcillin: use in infections involving anaerobic bacteria.

Eleven patients with serious infections involving anaerobic bacteria were treated with carbenicillin (four patients) or ticarcillin (seven patients). All patients were cured clinically and bacteriologically of their infections. An in vitro study testing 157 recently isolated anaerobic organisms against 11 antibiotics showed chloramphenicol, carbenicillin, and ticarcillin at blood level concentrations to be inhibitory to more anaerobic strains than the other eight antibiotics tested. Ticarcillin and carbenicillin appear to be safe and effective and deserve further consideration for use in the therapy of anaerobic infections.

Abdomen↗
PubMedDate not supplied

Histocompatibility antigens in paraplegic or quadriplegic patients with sacroiliac joint changes.

HLA typing for the A and B loci and radiographic examination of the sacroiliac joints were performed in 54 randomly selected patients with paraplegia or quadriplegia of more than 3 years' duration. The sacroiliac joints were abnormal in 24 patients. No association was found between any of the HLA antigens of the A and B loci and the sacroiliac joint changes. There was, however, an increased incidnece of sacroiliac joint changes in quadriplegic as compared to paraplegic patients.

Female↗
PubMedDate not supplied

Behçet's disease in a vaginal smear. Report of a case with cytologic features and their distinction from squamous cell carcinoma.

A 52-year-old woman who had undergone a hysterectomy 15 years previously for benign disease presented with ulcerative lesions on the perigenital skin and external genitalia. A Papanicolaou smear of the vagina, unaccompanied by any history, showed a heavy, purulent exudate and many isolated pleomorphic and keratinizing squamous cells. The findings were suggestive of squamous cell carcinoma. Subsequently obtained clinical data revealed a long-standing history of ulcerating oral and genital lesions of Behçet's disease. Biopsy confirmed the nonneoplastic ulcerative nature of the process. Given this cytologic pattern, the presence of a substantial purulent exudate and the identification of cytologic features suggesting reparative epithelial changes should caution the observer against an interpretation of squamous cell carcinoma and suggest the presence of a nonneoplastic ulcerative process.

Behcet Syndrome↗