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N J Patronas

Publications and source records attributed to N J Patronas.

95 records · Page 6Linked to original sources
PubMedDate not supplied

Ventricular septa in the neonatal age group: diagnosis and considerations of etiology.

Twenty-four patients with ventricular septa are discussed. Seventeen patients had septa acquired during the neonatal period and seven exhibited septations at birth (cogenital septa). Among the acquired septa, there were true intraventricular septa and septa that originated outside the ventricles but later became part of the ventricular system (pseudosepta). Pseudosepta originate in necrotic, cavitating periventricular white matter that, in temporal sequence, becomes ventricularized. Serial use of cranial sonography provided important information about the pathologic mechanisms that govern the development of septa. Intraventricular hemorrhage and infection are the major causes of true intraventricular septa, while periventricular leukomalacia serves as primary cause of pseudosepta. Sonography is the diagnostic method of choice. Septa are associated with a high incidence (62%) of shunt failure.

Brain Diseases↗
PubMedDate not supplied

Positron emission tomographic study of suppression of gray-matter glucose utilization by brain tumors.

Positron emission tomography (PET) scanning with [18F]-2-fluoro-2-deoxy-D-glucose (FDG) was used to study 59 patients with astrocytomas and three patients with other cerebral mass lesions. Suppression of gray-matter glucose utilization ranging from 8% to 64% (mean, 30%) was seen in 92% of cases. Three categories of suppression were apparent, with the greatest degrees of suppression occurring in edematous gray matter adjacent to mass lesions. Lesser degrees of suppression were noted in nonedematous structures (normal attenuation on computed tomographic scan) adjacent to the lesion. Significant suppression was also present in gray matter spatially remote from but functionally linked to the site of the lesion. This approach may become a useful tool for improved understanding of the clinical presentation of certain pathologic entities and for evaluation of disease progression and response to treatment.

Astrocytoma↗
PubMedDate not supplied

CT of subacute sclerosing panencephalitis.

Subacute sclerosing panencephalitis is a progressive, frequently fatal slow virus infection of the brain attacking children and young adults and caused by measles virus. Computed tomography (CT) of the brain in 15 patients with this disease was normal in seven and abnormal in eight. CT demonstrated varying degrees of cortical atrophy associated with focal and multifocal low density lesions of the white matter. Two cases demonstrated low density lesions of the caudate nuclei. The CT lesions were seen in chronic cases and reflect the gliosis and atrophy that occur in this disease. Differential diagnoses include other viral infections and demyelinating and dysmyelinating diseases. Diagnostic laboratory evaluation includes serum and cerebrospinal fluid titers for measles antibodies, cerebrospinal fluid protein electrophoresis, electroencephalography, and cranial CT.

Adolescent↗
PubMedDate not supplied

Clinical applications of combined cerebral angiograms and brain CT scans.

This paper illustrates the clinical value of a computer technique for superimposition of two different kinds of imaging procedures. The initial application was to overlay cerebral angiograms onto computed tomograms of the brain. Case material from three patients with intracerebral abnormalities is presented. The sum of information from the combined studies exceeds that from either study alone and has value for both diagnosis and treatment of head lesions.

Brain↗