Search PubMed⌕ Search

Biomedical subjects

N J Goddard

Publications and source records attributed to N J Goddard.

43 records · Page 3Linked to original sources
PubMed1984

Rotation osteotomy of the humerus for birth injuries of the brachial plexus.

The use of a rotation osteotomy of the humerus in 10 patients with disabling loss of lateral rotation at the shoulder due to brachial plexus birth injuries is described. The operative technique and complications are discussed. Before operation only one patient was independent, but after operation nine of them were. Restoration of lateral rotation at the shoulder can improve the function, the appearance and the independence of these handicapped patients.

Birth Injuries↗
PubMed1983

The monitoring of ascorbate and monoamine transmitter metabolites in the striatum of unanaesthetised rats using microprocessor-based voltammetry.

Voltammetry in vivo has suffered from the limitation that electrodes which give high resolution of the various electroactive compounds present in brain tissue have a short life span, and, conversely, that stable electrodes give poor resolution. Carbon paste electrodes and linear sweep voltammetry with semidifferentiation can resolve changes in the concentration of ascorbate, deaminated and methylated metabolites of catecholamines, and the 5-hydroxyindoles in vivo and give stable recordings over many weeks. However, these changes in concentration are difficult to quantify. We have now developed the method further with the application of microprocessor technology. Microprocessor-based voltammetry and data analysis enable one to quantify changes in the concentration of electroactive species in complex mixtures where there are no separate oxidation peaks for the components; this has been achieved both in vitro and in vivo. Changes in dopamine release from the striatum have been monitored continuously over 48 h in unanaesthetised rats after the intraperitoneal administration of haloperidol. Carbon paste electrodes and microprocessor-controlled linear sweep voltammetry facilitates the quantitative, continuous monitoring of the extracellular concentration of ascorbate, the deaminated and methylated metabolites of catecholamines, and the 5-hydroxyindoles in the brain of unrestrained animals.

3,4-Dihydroxyphenylacetic Acid↗
PubMedDate not supplied

Surgical treatment of the rheumatoid hand.

Many rheumatoid patients either present late or are denied access to surgery which would benefit them if undertaken at an early stage. Combined clinics involving physicians, surgeons and therapists allow better assessment and help patients to receive maximum benefit from treatment. An understanding of the principles of surgery of the rheumatoid hand is important in the management of these patients.

Arthritis, Rheumatoid↗
PubMedDate not supplied

Radial head fractures.

Radial head injuries commonly present to the accident and emergency department. They may be the manifestation of a more severe injury involving the forearm and wrist. An understanding of the classification and management of these injuries may prevent the development of a painful stiff elbow and wrist.

Adult↗