Search PubMed⌕ Search

Biomedical subjects

N Islam

Publications and source records attributed to N Islam.

At least 145 records · Page 8Linked to original sources
PubMed1978

Tinidazole and metronidazole in hepatic amoebiasis.

The efficacy of metronidazole and tinidazole has been compared in 31 patients with hepatic amoebiasis. Only those with unequivocal clinical, radiological and laboratory evidence of hepatic amoebiasis were included; diagnostic and therapeutic aspiration was performed where necessary. 15 patients received metronidazole and 16 tinidazole, in random order. The 2 groups were comparable. Both drugs were given orally in a single daily dose of 2g for a minimum of 3 days, with treatment extended if considered clinically advisable. 12 of 15 patients (80%) were cured with metronidazole given for an average period of 7 days (range 4 to 14 days). 15 of 16 patients (93.8%) given tinidazole were cured and the mean duration of treatment was 4 days (range 3 to 6 days). There were fewer side-effects with tinidazole. In this study of hepatic amoebiasis in Bangladesh, tinidazole was found to be superior to metronidazole in overall efficacy because a shorter course of treatment was necessary and it caused fewer side-effects.

Adolescent↗
PubMed1978

Amoebic liver abscess and clinical experiences with tinidazole in Bangladesh.

35 cases of amoebic liver abscess have been studied and their clinical diagnostic features analyzed. The diagnosis was based on WHO criteria of enlarged tender liver, leucocytosis and aspiration of typical anchovy sauce pus from the abscess. The authors have however, suggested major and minor diagnostic criteria for the condition. These cases were all treated with new nitroimidazole derivative Tinidazole in a single dose of 2 gm daily for consecutive 2 or 3 days. All the cases were followed up for at least 2 months. 100 per cent cure rate was observed. However, in 7 cases the dosage had to be repeated. Minor side effects were noted. The liver function tests and blood chemistry done pretreatment and post-treatment did not show any drug related toxicity.

Adolescent↗
PubMed1977

Two new methods of percussion.

Existing methods of percussion have been reviewed and their drawbacks enumerated. Two new methods of percussion, single hand, and four methods have been described. It has been claimed that the new methods of percussion are better than the existing methods.

Humans↗
PubMed1976

Mebendazole and pyrantel pamoate as broad-spectrum anthelmintics.

The efficacy of mebendazole and pyrantel pamoate was studied in two groups of 59 and 58 cases, respectively, of patients with polyparasitosis. Mebendazole had a cure rate of 96%, 82.2%, 71.4% and 66.6% in A. lumbricoides, hookworm, T. trichiura and S. stercoralis, respectively, while the corresponding figures for pyrantel pamoate were 92.6%, 85.7%, 19.4% and 0%. Pyrantel pamoate is considered to have no significant effect on T. trichiura and S. stercoralis. None of the drugs had any effect on T. saginata. Both drugs have been found to be equally effective against enterobiasis by various authors. It is recommended that pyrantel pamoate be the drug of choice in cases of multiple parasitic infections excluding T. trichiura and S. stercoralis whereas those with one or both of these in addition to others should be treated with mebendazole. Mebendazole can be prescribed for patients with clinical evidence of helminthic infections even where stool examination is not possible as it covers almost the whole range of common helminthic infections. The only limitation for poorer patients however is its cost. Pyrantel pamoate has a wider applicability for the poorer patients in spite of the fact that it is ineffective against trichurids and S. stercoralis.

Adolescent↗
PubMed1976

Echinococcosis in cattle and goats.

In the 500 cattles examined, 90 (18%) had hydatid cysts in one or more organs whereas only 12(2.4%) goats, out of 500 had the disease. This is considered to be due to shorter period of longevity and age of slaughter of goats compared to catte. Since dog is an important definitive host responsible for the spread of echinococcosis, a survey on the incidence of hydatid cyst in dogs is necessary from public health point of view.

Adult↗
PubMed1975

Echinococcosis in bangladesh.

A questionnaire sent out to eight medical college hospitals in Bangladesh revealed the observations of 18 cases of hydatid disease. Seven affected the lungs, another seven the liver, one both, in three the localization was on or behind the peritoneum. Of seven the nature was suspected beforehand, of eleven confirmed after exploration. The conditions for echinococcal disease are often favourable in Bangladesh. Our results contradict the common opinion that it is rare.

Adolescent↗
PubMed1975

Cirrhosis of liver in Bangladesh. (A preliminary report).

The incidence of cirrhosis of liver in Bangladesh, its possible aetiological factors and clinical features have been studied. This being the initial report, embraces the population of only two hospitals in Dacca viz., Institute of Postgraduate Medicine and Research (P.G. Hospital) and Sir Salimullah Medical College Hospital situated three and a half kilometers apart. In a population of 5889, a total of 154 cases (2.6%) of cirrhosis of liver have been recorded. Nutritional deficiency has been considered to be the important aetiological factor whereas alcoholism does not appear to have any significant role. Almost all the cases (94.2%) were non-alcoholic. Pattern of clinical features have been compared with those of other authors and variations recorded. Further study on an elaborate scale has been suggested.

Adolescent↗
PubMed1975

Ulcerative colitis in Bangladesh.

A total of 100 cases with chronic diarrhoea having no apparent cause were investigated. Fifty seven of these cases fulfilled the diagnostic criteria of ulcerative colitis. Fortyone of these 57 patients were treated for acute amoebic dysentery during the initial episodes of their illness. Since attack of acute amoebic dysentery is liable to produce post-dysenteric ulcerative colitis, it is possible that ulcerative colitis exist in this country in at least 2 forms, idiopathic and post-dysenteric.

Adolescent↗