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Biomedical subjects

N Iarŭmov

Publications and source records attributed to N Iarŭmov.

At least 19 recordsLinked to original sources
PubMed2004

[The role of bacterial translocation and endotoxemia in pathogenesis of obturation ileus, caused by colorectal carcinoma. Limulus test--a method for quick diagnostics of endotoxemia].

Colorectal carcinoma is one of most common diseases in human body. Often it is presented for the first time by its complicated forms--obturation, perforation, bleeding etc. Most common is the obturation of the large bowel. His clinic is caused not only by intoxication of carcinoma, but by massive flow of endotoxin in systemic circulation. In this publication we are trying to explain changes in human body and we offer a test for quick and early diagnosis--Limulus test.

Bacterial Translocation↗
PubMed2004

[Study on the efficacy of famotidine (Quamatel) in the complex treatment of erosive gastroduodenitis, stress stomach ulcer and peptic duodenal ulcer].

The haemorrhage of upper gastrointestinal tract is one of the serious problem in urgent surgery. Clinical effect of treatment with Quamatel purposely research was holded comparison of results in two groups patients. In group A with general medical treatment was included Quamatel--2 x 20 mg i.v. a day. In group B the patients was treated without H2 blocker. In cases of erosive gastritis was reported favorable effect in 76.47% at second day. The patients with stress stomach ulcer same effect was observed in third day--83.3%. In cases with peptic duodenal ulcer in I B--Forest group the bleeding was taken possession of 61.9%, in group II--79.31% and III--90.91% of patients.

Adult↗
PubMed2004

[Papillary and cystic tumor of pancreas--Frantz's tumor].

The aim of the authors is to introduce one rare known pathology which the Frantz's tumor is, his clinical characteristic, clinical signs, diagnostic and treatment. We have observed two separate cases of this illness in Clinic of Surgery (University Hospital "Queen Yoanna") in comparison with evidence of famous world surgeons. We have made an attempt to introduce one disease, which even though not often observed is significant by the fact that affect young women (girls) and only surgical resection is a treatment of choice.

Adolescent↗
PubMed2003

[Tactics and operative procedures in the management of complicated forms of malignant tumors of the left colon and rectum on emergency conditions].

Over the period 1996-2001, a total of 130 patients with complicated cancer of the left colon and 164 patients with complicated cancer of the rectum are subjected to treatment in the Clinic of Emergency Surgery at University Hospital "Queen Joanna", Sofia. Obturation is the commonest form of complication--136 patients (46.2%), followed by perforation either within the tumor or diastatic noted in 21 cases (7.1%), paratumor abscesses and infiltrates in 31 patients (10.5%) and rectohaemorrhage in 12 patients (4.0%). The optimal surgical approach to complicated forms of colorectal cancer of the left colon and rectum remains controversial especially when the patients underwent emergency surgery. Recently there has been a trend towards resection and anastomosis in selected patients. In each patient it's mandatory to make a precise and individual choice of the extend of the operative intervention, consistent with the patient's general condition and contributing to eliminate the life-endangering underlying cause. It must be realized by means of one-stage surgery when it's possible. Authors represent their personal experience with resolve of these actual problems.

Colonic Neoplasms↗
PubMed2002

[Surgical treatment of complicated gastrointestinal forms of non-Hodgkin lymphomas].

Authors represent their experience in surgical treatment of gastrointestinal forms of No-Hodgkin's lymphomas (NHL) combined with adjuvant therapy. We also represent an Ann Arbor Staging System and an Updated Kiel Classification. From 1991 to 2001 we analyzed 39 patients with different localization of gastro-intestinal NHL's lymphomas. In this aspect more common are stomach's lymphomas--27 patients (71%); small bowel's lymphomas--3 patients (8%); more uncommon are the localizations in colon--3 patients (8%), predominantly in caecum and right colon; rectum--3 patients (5%). Add to thus we described one mechanical icterus caused lymphoma, one multi-lobular spleen lymphoma and one case of anterior abdominal wall lymphoma. All patients underwent surgery. Eight of them were operated as an emergency cases. Operative treatment of NHL isn't radical but in combination with adjuvant therapy can be life saving event in complicated forms.

Combined Modality Therapy↗
PubMed2002

[Diagnostic puncture and puncture treatment of liver echinococcosis--"yes" or "no"].

The authors present as problematic and debatable the article about the diagnostic punction and punction treatment of the liver echinococcosis. Of many years scientific disputation about this problem exist. The risks of per cutaneum punction leads to many serious complications. This assess the revaluation of this method which must apply only in very limited evidence--small surface cysts without additional cysts and for diagnostic plan must be abandon.

Anaphylaxis↗
PubMed2000

[Preoperative staging on liver metastasis from colorectal carcinoma].

Preoperative staging of metastatic liver cancer (MLC) from colorectal carcinoma (CRC) is conducted with the purpose to identify potentially resectable MLC cases. Fifty-two patients undergo laparoscopic study (4.1% all endoscopies), and three--laparoscopic ultrasonography. Laparoscope E Wolf and 7.5 MHz linear transducer obtained from the Aloka Company are employed. The study covers 24 women and 28 men with mean age 61.6 years (range 23-87 y). MLC is diagnosed in 35.1% (13/37) of colonic, and in 73.3% (11/15) of rectal carcinoma cases. Furthermore, 69.3% of the patients (36/52) are in M-stage, accounted for by peritoneal or hepatic metastases. The size of lesions measures less than 2 cm in 25.0%, and less than 1 cm in 12.5% of the cases. Solitary metastasis is recorded in 8.3 per cent. In the event of isolated involvement of the left lobe the location of MLC is in the region of II-III segment. In one patient a single metastasis in VII segment, measuring 0.5/1.0 cm, missed by the imaging methods and laparoscopy, is documented by laparoscopic ultrasonography. Echographic diagnosis proves inaccurate in 16.7%, and false negative--in 12.5 per cent. In further three patients (12.5%) the conclusion reached is uncertain, with primary liver cancer being also considered. In 23.1% MLC from colonic carcinoma is situated entirely intrahepatally, and is not accessible to endoscopic inspection without laparoscopic and/or intraoperative ultrasonography; the latter is indicated in all T3 and T4 patients. Potential resectability is established in 16.7% of cases with liver metastases from CRC.

Adult↗
PubMed2000

[Risk of drug-induced acute pancreatitis following propofol anesthesia used in abdominal operations].

The postoperative pancreatitis is a well-known complication. More than eighty-five drugs have been reported to have induced postoperative pancreatitis. Twenty-five cases of Propofol-induced pancreatitis have been reported till now. The relation of pancreatitis to Propofol (Diprivan; Zeneca; London, UK) is considered as a possible one, but has been proved. The goal of the authors is to reveal the plasma lipid and amylase level dynamics in patients after Propofol anaesthesia. The clinicians have to consider this possible relation, because of the growing use of Propofol recently.

Abdomen↗
PubMed1999

[The pathomorphology of complicated colorectal cancer and the stages in the development of the tumor process].

A comprehensive pathomorphological assessment is done in 385 patients presenting complicated colorectal carcinoma, covering the period 1990 through 1995. The patients are distributed in 4 groups according to stage, with those in stage III being the most numerous--141 cases. The growth pattern of the neoplasm is as follows: exophytic growth--110 cases, ulcerous growth--57, cup-like growth--13, and endophytic growth--205 cases. On establishing metastatic lymph nodes within I and II lymph collectors, prophylactic postoperative chemo- and immunotherapy are undertaken. In case of lymph nodes present in III lymph collector, the operation is taken to be relatively radical, and for that reason chemo- and immunotherapy assume a therapeutic character.

Adenocarcinoma↗
PubMed1999

[The long-term results in complicated colorectal cancer (survival for over 3 and 5 years)].

Colorectal cancer survival depends on: stage of primary neoplastic process development, clinical complication pattern and clinical course of the disease, type (radicalism) of the surgical intervention done and histological verification of blastoma. As shown by the results, postoperative lethality in complicated colorectal carcinoma cases amounts to 17.1 per cent, whereas in those undergoing radical surgery for uncomplicated carcinoma it amounts to 6.8 per cent. Patients presenting complicated colorectal carcinoma are admitted to the clinic with diagnosis advanced stage of development of the disease which explains the lower survival rate. The studies performed show that five-year survivorship in patients with complicated colorectal carcinoma amounts to 33.3 per cent, while among those operated for uncomplicated colorectal carcinoma it is 62.7 per cent in the average.

Actuarial Analysis↗
PubMed1999

[The topographic anatomical aspects of some kidney anomalies].

On 50 cases of the dissecting material of the Department of Anatomy and Histology were worked out the kidney's vessels, the basin and the ureters, as the varieties in number and situation of the vessels, the cases of nephric ectopy and comparatively rare case of combined anomaly as well were traced and described. This anomaly is expressed in bilateral nephric ectopy, bilateral double ureter, which begins from independent calices set, and four pairs of polar kidney arteriae, which are situated bilateral as well. In the right they pass before v. cava inf. The vessels are equally calibrated, as the three pairs are branches of aorta abdominalis and the fourth of a. iliaca comm. The cases which were described attract the surgeons' interest because the zone of the kidney, its vessels and the way of the ureter are an object of frequent surgical interventions.

Arteries↗
PubMed1999

[Large-intestine perforations caused by primary colorectal cancer].

Twenty-seven cases of perforation, produced by primary colorectal carcinoma over the period 1993-1998, are described. The underlying causes of colorectal carcinoma complication and types of perforations observed are discussed. This is a report on personal experience with the therapeutic approach and operative management of this severest complication of colorectal carcinoma.

Colonic Diseases↗
PubMed1999

[Diaphragmatic hernias--the clinico-anatomical aspects].

The present research has been taken over 56 cadavers from the dissecting material of the Department of Anatomy and Histology in the time of four dissecting courses. Tissue defects of the diaphragma with or without diaphragmatic hernias has been searched for. Also it has been followed the frequency of the sliding and the paraesophageal hiatus hernias. The tissue changes has been carefully described. In 12 of the cases it has been determinate defects of the diaphragma, as in two of the cases has been found parahiatal hernias as well. In 7 of the cases it has been found relatively wide hiatus esophageus, as 3 of them were accompanied with hiatus hernias. It has been determinate one case with combined defect--hiatal and parahiatal hernia. It has been discuss the possible reasons for their appearance and simply anatomical aspects of the surgical correcting techniques, which are known to us.

Diaphragm↗
PubMed1999

[The treatment problems in complicated forms of colorectal cancer].

This is a literature survey on all complicated forms of colorectal carcinoma. A detailed assessment is done of emergency diagnostics in patients presenting complicated forms of colorectal carcinoma. Proceeding from numerous literature reports on the issue, the current views on the tactics and operative approach to complicated forms of colorectal carcinoma are outlined. Patients with complicated CR carcinoma are with poor prognosis, as compared to those with uncomplicated lesion. Intraoperative lethality is much higher, and not infrequently oncologic development grade IV (metastatic disease) is established during operative intervention. The 5-year survivorship among colorectal carcinoma patients is much lower by comparison with that in uncomplicated carcinoma cases.

Aged↗
PubMed1999

[Tactics and operative methods in treating complicated colorectal cancer].

Over the period 1993-1998, a total of 385 patients with complicated colorectal cancer are subjected to treatment in the clinic of emergency surgery--University Hospital "Queen Giovanna", Sofia. Obturation is the commonest form of complication--43.8 per cent, perforation within the tumor or diastasis noted in 27 cases (7.01%), paratumor abscesses and infiltrates--in 8.3 per cent and rectohemorrhage--in 4.2 per cent. The therapeutic and operative approach, and the scope of surgery are dependent on a multitude of factors which should be given due consideration by the surgeon. In each patient presenting complicated colorectal carcinoma it is mandatory to make a precise and individual choice of the extent of operative intervention, consistent with the patient's general condition and contributing to eliminate the life-endangering underlying cause.

Colorectal Neoplasms↗