Search PubMed⌕ Search

Biomedical subjects

N I Berezhnova

Publications and source records attributed to N I Berezhnova.

6 recordsLinked to original sources
PubMed1990

[Effects of dalargin on proliferative processes and vertical migration of cells of the corneal epithelium during stress].

We studied the effect of synthetic analogue of opioid peptides dalargin on kinetics of cell population of corneal epithelium during stress. It was found out that dalargin introduction before stress decreased the level of pathological mitoses induced by the acute stress action in white rats early in the morning. Dalargin prevented the activation of the proliferative process after the repeated stress activation, made stress milder. The stress induced vertical migration of the cells of the corneal epithelium normalized by dalargin. We believe these results show that dalargin has a good protective effect.

Animals↗
PubMed1985

[Acceleration of the vertical migration of corneal epithelial cells in white rats under chronic immobilization stress].

Autoradiography with 3H-thymidine was employed to study DNA synthesis and the rate of the migration of labeled nuclei from the basal layer to the surface layers of albino rat corneal epithelium after repeated immobilization stress. The studies were performed at once, and 24 and 72 hours after 3H-thymidine injection. Post-stressor activation of DNA synthesis and acceleration of the vertical migration of the cells were recorded.

Animals↗
PubMed1984

[Activation of cell division and nucleic acid synthesis in the corneal epithelium of white rats undergoing repeated exposure to stress].

A study was made of the influence of single and repeated stress on the mitotic activity and synthesis of DNA and RNA in the corneal epithelium of albino rats. The stressors used were fixation on the back during one hour, the influence of 1.5-h hyperthermia (41.5 degrees C), and the influence of hypoxia (4h, 9000 m). Single stress induced the depression of the mitotic activity. The autography tests of DNA synthesis were made constantly. Repeated stress (5 exposures) entailed activation of the synthesis of the nucleic acids and cell division, evidence of a structural trace of stress, in the epithelial tissues.

Adaptation, Physiological↗