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Biomedical subjects

N I Amosenkova

Publications and source records attributed to N I Amosenkova.

At least 19 recordsLinked to original sources
PubMed1979

[Combined use of serological tests for the purpose of the diagnosis and study of Q-rickettsiosis].

The combined use of the complement fixation test, the indirect immunofluorescent test and the ring precipitation test with C. burnetii antigen greatly enhances the effectiveness or serological study, as it allows not only to find out the spread of infection among population more completely, but also to differentiate, to a certain extent, "fresh" infectious process from immunological trace reaction. The arguments are presented in favor of introducing the antigen of C. burnetii, phase I, into practice, especially in surveying the sera of farm animals.

Animals↗
PubMed1976

[Q fever].

Explore the source record for details and available documents.

Animals↗
PubMed1974

Infectious process in the lungs after intranasal challenge of white mice with Rickettsia prowazekii. A histologic immunoluminescent and electron microscopic study.

The lungs of white mice given intranasal injections of various amounts of Rickettsia prowazekii were studied. Agent parasitism, mainly in the alveolar epithelium and nonciliated cells of bronchiolar epithelium, underlies the infectious process developing in the lungs. Rickettsiae may lodge in these cells without inducing both local and general alterations or a leukocyte response. After being released from the cells they inhabit, rickettsiae evoke acute exudative inflammation. The inflammation is accompanied by marked circulatory disorders, necrosis of exudate cells and vascular thrombosis, which are induced by toxic products of the agent. Polymorphonuclear leukocytes and macrophages represent the main defense mechanism of a host. They ingest and destroy rickettsial organisms. If infection runs a favorable course, phagocytes destroy the rickettsiae, and the organisms are entirely cleared from the lungs.

Administration, Intranasal↗